Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.56 |
| ▸ | NFATC1 | O95644 | 1/20 | 0.56 |
| ▸ | ABL1 | P00519 | 5/20 | 0.53 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.51 |
| ▸ | CYP11B2 | P19099 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.44 |
| ▸ | WNT1 | P04628 | 1/20 | 0.43 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.42 |
| ▸ | WNT3A | P56704 | 1/20 | 0.42 |
| ▸ | CCNC | P24863 | 1/20 | 0.41 |
| ▸ | CDK8 | P49336 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.41 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.41 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C8 | P10632 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18174642 | 0.81 | DHODH (0.46) | DYRK1ANFATC1ABL1CYP11B1CYP11B2 | |
| SCHEMBL18174787 | 0.81 | DHODH (0.46) | DYRK1ANFATC1ABL1CYP11B1CYP11B2 | |
| SCHEMBL18174718 | 0.80 | CYP17A1 (0.44) | DYRK1ANFATC1ABL1CYP11B1CYP11B2 | |
| SCHEMBL14900842 | 0.80 | CYP11B1 (0.51) | DYRK1ANFATC1ABL1CYP11B1CYP11B2 | |
| SCHEMBL21105125 | 0.80 | RPS6KA3 (0.54) | DYRK1ANFATC1UHRF1WNT3ACCNC | |
| SCHEMBL18899879 | 0.78 | ABL1 (0.74) | ABL1CYP11B1CYP11B2 | |
| SCHEMBL30947586 | 0.78 | ABL1 (0.47) | ABL1CYP11B1CYP11B2CYP1A2CYP17A1 | |
| SCHEMBL15161092 | 0.78 | CYP17A1 (0.47) | DYRK1ANFATC1ABL1CYP11B1CYP11B2 | |
| SCHEMBL22426647 | 0.77 | PDK2 (0.47) | DYRK1ANFATC1CYP1A2UHRF1CCNC | |
| SCHEMBL30906620 | 0.76 | DYRK1A (0.51) | DYRK1ANFATC1CYP11B1CYP11B2WNT3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210387982-A1 | HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2021-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210387982-A1 | HETEROCYCLIC KINASE INHIBITORS AND USES THEREOF | LCK, SRC, CILK1 | DYRK1A 131/4885NFATC1 384/4885ABL1 8/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.