Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 2/20 | 0.59 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.57 |
| ▸ | MAPT | P10636 | 1/20 | 0.57 |
| ▸ | DAO | P14920 | 1/20 | 0.57 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.57 |
| ▸ | MAOB | P27338 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.51 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.51 |
| ▸ | FAAH | O00519 | 1/20 | 0.50 |
| ▸ | HRH4 | Q9H3N8 | 2/20 | 0.49 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.49 |
| ▸ | IDO1 | P14902 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7030607 | 0.95 | FLT3 (0.57) | FLT3PDGFRBPDGFRAKDM4EHPGD | |
| SCHEMBL7024844 | 0.93 | FLT3 (0.62) | FLT3PDGFRBPDGFRAKDM4EHPGD | |
| SCHEMBL24588742 | 0.79 | HRH4 (0.52) | KDM4EHPGDHSD17B10MAPTDAO | |
| SCHEMBL27743091 | 0.78 | FLT3 (0.51) | FLT3PDGFRBPDGFRAKDM4EHPGD | |
| SCHEMBL75198 | 0.77 | MLLT1 (0.65) | FLT3KDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL5514494 | 0.77 | PDGFRB (0.65) | FLT3PDGFRBPDGFRAKDM4EHPGD | |
| Indole-2-Carboxylic Acid SCHEMBL28171743 | 0.76 | KDM4E (0.89) | FLT3PDGFRBPDGFRAKDM4EHPGD | |
| SCHEMBL6170688 | 0.76 | HRH4 (0.57) | FLT3PDGFRBDAOALDH1A1HRH4 | |
| SCHEMBL24588682 | 0.76 | KCNH2 (0.60) | KDM4EHSD17B10ALDH1A1HRH4HRH3 | |
| SCHEMBL29446300 | 0.75 | PTPN2 (0.72) | FLT3PDGFRBPDGFRAKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2948454-B1 | TRIAZINE COMPOUNDS AND A PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENT & IND RES AN INDIAN REGISTERED BODY INCORPORATED UNDER THE REGISTRATION OF SOCIETI (IN) | 2017-05-31 | — | — | EP | disclosed |