Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 9/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18900833 | 0.90 | CMA1 (0.55) | CMA1SMN1; SMN2RECQLL3MBTL1MAPT | |
| SCHEMBL7961041 | 0.84 | CMA1 (0.80) | CMA1SMN1; SMN2RECQLL3MBTL1MAPT | |
| SCHEMBL1849731 | 0.81 | CMA1 (0.79) | CMA1SMN1; SMN2RECQLL3MBTL1MAPT | |
| SCHEMBL7960485 | 0.81 | CMA1 (0.84) | CMA1SMN1; SMN2RECQLL3MBTL1MAPT | |
| SCHEMBL7960524 | 0.74 | CMA1 (1.00) | CMA1POLB | |
| SCHEMBL7951279 | 0.71 | CMA1 (1.00) | CMA1 | |
| SCHEMBL1851671 | 0.70 | CMA1 (1.00) | CMA1SMN1; SMN2POLB | |
| SCHEMBL1851876 | 0.68 | CMA1 (0.83) | CMA1SMN1; SMN2L3MBTL1MAPTCYP1A2 | |
| SCHEMBL18900835 | 0.67 | CMA1 (0.74) | CMA1POLB | |
| SCHEMBL1850267 | 0.67 | CMA1 (0.61) | CMA1SMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323991-B1 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2017-05-31 | — | — | EP | disclosed |