Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 16/20 | 0.54 |
| ▸ | CNR1 | P21554 | 3/20 | 0.54 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 2/20 | 0.43 |
| ▸ | SRC | P12931 | 2/20 | 0.43 |
| ▸ | FLT3 | P36888 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18557484 | 0.91 | CNR2 (0.54) | CNR2CNR1HRH3SRCFLT3 | |
| SCHEMBL16212528 | 0.86 | CNR2 (0.75) | CNR2CNR1 | |
| SCHEMBL16212195 | 0.86 | CNR2 (0.75) | CNR2CNR1 | |
| SCHEMBL16212196 | 0.86 | CNR2 (0.75) | CNR2CNR1 | |
| SCHEMBL18900564 | 0.86 | CNR2 (0.56) | CNR2CNR1HRH3FYNSRC | |
| SCHEMBL16228919 | 0.85 | CNR2 (0.65) | CNR2CNR1 | |
| SCHEMBL18900884 | 0.84 | HRH3 (0.47) | CNR2CNR1HRH3FYNSRC | |
| SCHEMBL20171901 | 0.84 | CNR2 (0.75) | CNR2CNR1 | |
| SCHEMBL18900887 | 0.80 | CNR2 (0.55) | CNR2CNR1HRH3FYNSRC | |
| SCHEMBL18900596 | 0.80 | CNR2 (0.55) | CNR2CNR1HRH3FYNSRC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2991988-B1 | PYRROLO[2,3-D]PYRIMIDINE DERIVATIVES AS CB2 RECEPTOR AGONISTS | HOFFMANN LA ROCHE (CH) | 2017-05-31 | — | — | EP | disclosed |