Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CMA1 | P23946 | 6/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | GLA | P06280 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18900696 | 0.83 | CMA1 (0.52) | CMA1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18900943 | 0.83 | CMA1 (0.53) | CMA1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18900819 | 0.82 | CMA1 (0.52) | CMA1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18900859 | 0.82 | GPR84 (0.52) | CMA1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL18900860 | 0.81 | CMA1 (0.52) | CMA1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL6115201 | 0.81 | CMA1 (0.54) | CMA1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7963167 | 0.79 | CMA1 (0.49) | CMA1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7965706 | 0.76 | CMA1 (0.44) | CMA1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7960283 | 0.75 | CMA1 (0.65) | CMA1TSHRCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL7950640 | 0.74 | CMA1 (0.44) | CMA1TSHRCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2323991-B1 | CHYMASE INHIBITORS | BOEHRINGER INGELHEIM INT (DE) | 2017-05-31 | — | — | EP | disclosed |