Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 6/20 | 0.59 |
| ▸ | GAA | P10253 | 5/20 | 0.53 |
| ▸ | NPC1 | O15118 | 6/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 5/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.49 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12690279 | 0.81 | KCNMA1 (0.72) | KCNMA1GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL1024037 | 0.81 | MEN1 (0.56) | KCNMA1GAAHDAC1KMT2AMEN1 | |
| SCHEMBL6029542 | 0.79 | KCNMA1 (0.84) | KCNMA1GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL2605540 | 0.78 | KCNMA1 (0.82) | KCNMA1GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL14363234 | 0.78 | KCNMA1 (0.72) | KCNMA1GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL2605548 | 0.78 | KCNMA1 (0.82) | KCNMA1GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL259371 | 0.77 | KMT2A (0.66) | NPC1SMN1; SMN2TP53KMT2AMEN1 | |
| SCHEMBL19417885 | 0.76 | GSK3B (0.63) | NPC1RAB9AMAPT | |
| SCHEMBL18027729 | 0.75 | KCNMA1 (0.71) | KCNMA1GAANPC1SMN1; SMN2TP53 | |
| SCHEMBL10873010 | 0.75 | KCNMA1 (1.00) | KCNMA1GAANPC1SMN1; SMN2TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2274983-B1 | HARMFUL ARTHROPOD CONTROL COMPOSITION, AND FUSED HETEROCYCLIC COMPOUND | SUMITOMO CHEMICAL CO (JP) | 2017-05-31 | — | — | EP | disclosed |