SCHEMBL189010

SCHEMBL189010

Cc1ccc(Cl)cc1Br

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30118252 1.00
SCHEMBL31433485 0.83
SCHEMBL560087 0.81 ALOX5 (0.43)
SCHEMBL29427169 0.79
SCHEMBL531769 0.79
SCHEMBL14993676 0.77 CYP3A4 (0.44)
Fluoride SCHEMBL27894203 0.77 CYP3A4 (0.44)
SCHEMBL91997 0.75
SCHEMBL31556280 0.75
SCHEMBL30030367 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119841705-A Preparation method of 2-bromo-4-chloro-3-fluorotoluene 浙江凯普化工有限公司 2025-04-18 CN claimed
CN-113979835-B Synthesis method of pazopanib trimer impurity intermediate 重庆医科大学 2023-09-26 CN claimed
CN-113979835-A Synthetic method of pazopanib trimer impurity intermediate 重庆医科大学 2022-01-28 CN claimed
CN-111253223-A Triarylmethane derivatives with large steric hindrance and synthesis method thereof 重庆医科大学 2020-06-09 CN claimed
CN-108707112-A A kind of preparation method of antidepressant agents impurity isomers chlorine nitre phenyl intermediates 刘可 2018-10-26 CN claimed
CN-108409659-A A kind of preparation method of antidepressant agents impurity isomers key intermediate 刘可 2018-08-17 CN claimed
CN-108409660-A A kind of preparation method of antidepressant agents impurity isomers 刘可 2018-08-17 CN claimed
EP-1928928-B1 METHOD FOR THE PRODUCTION OF POLYISOCYANATES HUNTSMAN INT LLC (US) 2018-02-21 EP claimed
US-20080249202-A1 Method for the Production of Polyisocyanates HUNTSMAN INTERNATIONL LLC (US) 2008-10-09 US claimed
EP-1928928-A1 METHOD FOR THE PRODUCTION OF POLYISOCYANATES HUNTSMAN INTERNATIONAL LLC (US) 2008-06-11 EP claimed
WO-2007039362-A1 METHOD FOR THE PRODUCTION OF POLYISOCYANATES HUNTSMAN INTERNATIONAL LLC (US) 2007-04-12 WO claimed
US-20070065360-A1 Nonpolar thymidine analogs NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT 2007-03-22 US claimed
JP-54151945-A None JP disclosed
EP-4626870-A1 NONCOVALENT KEAP1-NRF2 SMALL-MOLECULE INHIBITORS University of Copenhagen (DK) 2025-10-08 EP disclosed
US-12435060-B2 Acylamino bridged heterocyclic compound, and composition and application thereof BEIJING SCITECH-MQ PHARMACEUTICALS LIMITED (CN) 2025-10-07 US disclosed
US-20250179059-A1 ANTICANCER COMPOUNDS THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2025-06-05 US disclosed
US-4593033-A Cardiovascular disorders MERCK & CO., INC. (US) 1986-06-03 US disclosed
JP-S54151945-A PREPARATION OF 6-CHLORO-3-TOLUIDINE-4-SULFONIC ACID HODOGAYA CHEM CO LTD 1979-11-29 JP disclosed
US-4029592-A ANHYDRIDED, HALOGENATED HYDROCARBON, TARRY BY-PRODUCT SUPPRESSANTS STANDARD OIL COMPANY (INDIANA) (US) 1977-06-14 US disclosed
US-3960900-A POLYBUTENE, MALEIC ANHYDRIDE STANDARD OIL COMPANY (US) 1976-06-01 US disclosed