Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 16/20 | 0.55 |
| ▸ | CCR5 | P51681 | 5/20 | 0.55 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.42 |
| ▸ | SLC6A7 | Q99884 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18901623 | 1.00 | CCR2 (0.55) | CCR2CCR5KCNH2PKMSLC6A7 | |
| SCHEMBL18901697 | 0.90 | CCR2 (0.54) | CCR2CCR5KCNH2PKMSLC6A7 | |
| SCHEMBL18901636 | 0.87 | CCR2 (0.53) | CCR2CCR5KCNH2PKMSLC6A7 | |
| SCHEMBL18901839 | 0.83 | CCR2 (0.57) | CCR2CCR5KCNH2 | |
| SCHEMBL18901428 | 0.83 | CCR2 (0.57) | CCR2CCR5KCNH2 | |
| SCHEMBL18901708 | 0.83 | CCR2 (0.57) | CCR2CCR5KCNH2 | |
| SCHEMBL14037099 | 0.83 | CCR2 (0.54) | CCR2CCR5KCNH2PKMSLC6A7 | |
| SCHEMBL3325003 | 0.82 | CCR2 (0.66) | CCR2CCR5KCNH2 | |
| SCHEMBL13335024 | 0.82 | CCR2 (0.66) | CCR2CCR5KCNH2 | |
| SCHEMBL14011061 | 0.81 | CCR2 (0.82) | CCR2CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |