Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 20/20 | 0.70 |
| ▸ | CCR5 | P51681 | 14/20 | 0.70 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13361939 | 1.00 | CCR2 (0.70) | CCR2CCR5KCNH2 | |
| SCHEMBL3326201 | 1.00 | CCR2 (0.70) | CCR2CCR5KCNH2 | |
| SCHEMBL3326342 | 0.84 | CCR2 (0.84) | CCR2CCR5 | |
| SCHEMBL13361937 | 0.84 | CCR2 (0.84) | CCR2CCR5 | |
| SCHEMBL3330402 | 0.84 | CCR2 (0.84) | CCR2CCR5 | |
| SCHEMBL3327106 | 0.82 | CCR2 (1.00) | CCR2CCR5KCNH2 | |
| SCHEMBL3360369 | 0.82 | CCR2 (1.00) | CCR2CCR5KCNH2 | |
| SCHEMBL13361832 | 0.82 | CCR2 (1.00) | CCR2CCR5KCNH2 | |
| SCHEMBL3326295 | 0.82 | CCR2 (1.00) | CCR2CCR5KCNH2 | |
| SCHEMBL13361938 | 0.82 | CCR2 (1.00) | CCR2CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |