Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 17/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 8/20 | 0.53 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | CCR5 | P51681 | 2/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13334958 | 0.87 | CCR2 (0.70) | CCR2KCNH2FFAR4HRH3MAPT | |
| SCHEMBL3025216 | 0.87 | CCR2 (0.70) | CCR2KCNH2FFAR4HRH3MAPT | |
| SCHEMBL18901619 | 0.87 | CCR2 (0.70) | CCR2KCNH2FFAR4HRH3MAPT | |
| Hydrochloric Acid SCHEMBL4276553 | 0.86 | CCR2 (0.69) | CCR2KCNH2FFAR4HRH3MAPT | |
| Hydrochloric Acid SCHEMBL4153397 | 0.86 | CCR2 (0.69) | CCR2KCNH2FFAR4HRH3MAPT | |
| SCHEMBL13335001 | 0.86 | CCR2 (0.53) | CCR2KCNH2FFAR4HRH3MAPT | |
| SCHEMBL13335014 | 0.86 | CCR2 (0.62) | CCR2KCNH2FFAR4CCR5 | |
| Hydrochloric Acid SCHEMBL3326153 | 0.85 | CCR2 (0.61) | CCR2KCNH2FFAR4CCR5 | |
| Hydrochloric Acid SCHEMBL3324710 | 0.85 | CCR2 (0.61) | CCR2KCNH2FFAR4CCR5 | |
| Hydrochloric Acid SCHEMBL3327112 | 0.85 | CCR2 (0.52) | CCR2KCNH2FFAR4HRH3MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |