Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 18/20 | 0.56 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.56 |
| ▸ | CCR5 | P51681 | 13/20 | 0.53 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.45 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18901809 | 0.89 | CCR2 (0.54) | CCR2KCNH2CCR5PIK3CDPIK3CA | |
| SCHEMBL18901614 | 0.88 | CCR2 (0.67) | CCR2CCR5POLB | |
| SCHEMBL18901618 | 0.88 | CCR2 (0.67) | CCR2CCR5POLB | |
| SCHEMBL18901839 | 0.83 | CCR2 (0.57) | CCR2KCNH2CCR5 | |
| SCHEMBL18901568 | 0.83 | CCR2 (0.46) | CCR2KCNH2CCR5 | |
| SCHEMBL18901428 | 0.83 | CCR2 (0.57) | CCR2KCNH2CCR5 | |
| SCHEMBL18901708 | 0.83 | CCR2 (0.57) | CCR2KCNH2CCR5 | |
| SCHEMBL3324355 | 0.81 | CCR2 (0.82) | CCR2KCNH2CCR5 | |
| SCHEMBL13334960 | 0.81 | CCR2 (0.82) | CCR2KCNH2CCR5 | |
| SCHEMBL18901678 | 0.79 | CCR2 (0.44) | CCR2KCNH2PIK3CDPIK3CAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763351-B9 | 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS | INCYTE HOLDINGS CORP (US) | 2017-05-31 | — | — | EP | disclosed |