Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.51 |
| ▸ | MC3R | P41968 | 2/20 | 0.51 |
| ▸ | MC1R | Q01726 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | DPP4 | P27487 | 1/20 | 0.43 |
| ▸ | FAP | Q12884 | 1/20 | 0.43 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19258607 | 0.79 | PREP (0.63) | L3MBTL1SMN1; SMN2TSHR | |
| SCHEMBL12599420 | 0.79 | ALDH1A1 (0.68) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL27918437 | 0.79 | MC4R (0.53) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL474618 | 0.79 | ACE (0.60) | MC4RMC3RMC1RALDH1A1L3MBTL1 | |
| SCHEMBL3462006 | 0.79 | MC4R (0.53) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL3462009 | 0.79 | ALDH1A1 (0.68) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL474742 | 0.79 | ACE (0.60) | MC4RMC3RMC1RALDH1A1L3MBTL1 | |
| SCHEMBL10507780 | 0.78 | MC4R (0.55) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL10510159 | 0.78 | MC4R (0.52) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL10507773 | 0.78 | MC4R (0.55) | MC4RMC3RMC1RALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |