Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MC4R | P32245 | 2/20 | 0.51 |
| ▸ | MC3R | P41968 | 2/20 | 0.51 |
| ▸ | MC1R | Q01726 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 4/20 | 0.48 |
| ▸ | TACR3 | P29371 | 1/20 | 0.46 |
| ▸ | PREP | P48147 | 1/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL474618 | 0.88 | ACE (0.60) | MC4RMC3RMC1RALDH1A1L3MBTL1 | |
| SCHEMBL474742 | 0.88 | ACE (0.60) | MC4RMC3RMC1RALDH1A1L3MBTL1 | |
| SCHEMBL28650436 | 0.87 | ACE (0.58) | MC4RMC3RMC1RALDH1A1L3MBTL1 | |
| SCHEMBL10173178 | 0.85 | ALDH1A1 (0.52) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL2177077 | 0.85 | DPP4 (0.57) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL474918 | 0.85 | DPP4 (0.57) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL12798848 | 0.84 | ACE (0.55) | ALDH1A1KDM4EPOLBL3MBTL1GLA | |
| SCHEMBL13388251 | 0.83 | ALDH1A1 (0.50) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL13191239 | 0.83 | MC4R (0.49) | MC4RMC3RMC1RALDH1A1KDM4E | |
| SCHEMBL10222753 | 0.83 | MC4R (0.49) | MC4RMC3RMC1RALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2328865-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2017-05-31 | — | — | EP | disclosed |