Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 8/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 7/20 | 0.56 |
| ▸ | NPC1 | O15118 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 4/20 | 0.55 |
| ▸ | MAPT | P10636 | 4/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | NLRP1 | Q9C000 | 1/20 | 0.53 |
| ▸ | POLB | P06746 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NAMPT | P43490 | 1/20 | 0.53 |
| ▸ | LSS | P48449 | 1/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4587990 | 0.84 | CNR1 (0.67) | CNR1ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL8578118 | 0.81 | CNR1 (0.73) | CNR1ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL11051084 | 0.80 | CNR1 (0.83) | CNR1RAB9ANPC1SMN1; SMN2 | |
| SCHEMBL11767273 | 0.79 | NAMPT (0.57) | CNR1ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL10585478 | 0.78 | CNR1 (0.69) | CNR1ALDH1A1RAB9ANPC1MAPT | |
| SCHEMBL21252662 | 0.78 | KMT2A (0.65) | CNR1ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL14424476 | 0.77 | EPHX1 (0.71) | CNR1ALDH1A1SMN1; SMN2HTTLMNA | |
| SCHEMBL4741253 | 0.77 | MEN1 (0.76) | CNR1ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL11048619 | 0.77 | MEN1 (0.76) | CNR1ALDH1A1RAB9ANPC1MEN1 | |
| SCHEMBL6025181 | 0.77 | CNR1 (0.62) | CNR1ALDH1A1RAB9ANPC1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2900674-B1 | COMPOUNDS AND METHODS FOR PREVENTING, TREATING AND/OR PROTECTING AGAINST SENSORY HAIR CELL DEATH | UNIV WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) | 2017-05-31 | — | — | EP | disclosed |