SCHEMBL4741253

SCHEMBL4741253

O=C(Nc1ccc(Cl)cc1)Nc1ccc(Cl)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.76
KMT2A Q03164 5/20 0.76
ALDH1A1 P00352 1/20 0.75
NPC1 O15118 5/20 0.73
RAB9A P51151 4/20 0.73
HTT P42858 3/20 0.73
MAPT P10636 2/20 0.73
LMNA P02545 2/20 0.73
NLRP3 Q96P20 2/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
NLRP1 Q9C000 1/20 0.73
EPHX1 P07099 1/20 0.73
ADORA3 P0DMS8 1/20 0.73
CHRM1 P11229 1/20 0.73
SLC6A2 P23975 1/20 0.73
PDE4A P27815 1/20 0.73
EPHX2 P34913 1/20 0.73
ADRA1A P35348 1/20 0.73
OPRM1 P35372 1/20 0.73
PDE3A Q14432 1/20 0.73

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11048619 1.00 MEN1 (0.76) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL5650525 0.91 MAOA (0.67) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL11054644 0.91 CNR1 (0.74) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL4105004 0.91 CNR1 (0.74) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL11055930 0.89 CNR1 (0.70) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL14758356 0.89 MEN1 (0.75) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL3026575 0.89 RAB9A (0.70) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL17119070 0.89 RAB9A (0.70) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL4548119 0.89 CNR1 (0.70) MEN1KMT2AALDH1A1NPC1RAB9A
SCHEMBL14107061 0.89 GRIK1 (0.64) MEN1KMT2AALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1549730-A1 DISINFECTANT CLEANING COMPOSITIONS Reckitt Benckiser Inc. (US) 2005-07-06 EP claimed
WO-2004035723-A1 DISINFECTANT CLEANING COMPOSITIONS RECKITT BENCKISER INC (US) 2004-04-29 WO claimed
EP-4734912-A2 HIGH SEPARATION DUAL PHASE EYE MAKE-UP REMOVER Mary Kay, Inc. (US) 2026-05-06 EP disclosed
WO-2026087386-A1 ROSIN DIESTER COMPOUNDS AND USES THEREOF FIRMENICH SA (CH) 2026-04-30 WO disclosed
EP-4731171-A2 MINERAL FACIAL SUNSCREEN Mary Kay, Inc. (US) 2026-04-29 EP disclosed
EP-4724153-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE Mary Kay, Inc. (US) 2026-04-15 EP disclosed
US-20260090980-A1 COSMETIC COMPOSITIONS AND METHODS OF USING THE SAME MARY KAY INC. (US) 2026-04-02 US disclosed
US-20260083659-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE MARY KAY INC. (US) 2026-03-26 US disclosed
WO-2025264660-A1 COSMETIC COMPOSITION COMPRISING CAFFEINE AND MELATONIN MARY KAY INC. (US) 2025-12-26 WO disclosed
US-20250387310-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT FIRMENICH INCORPORATED (US) 2025-12-25 US disclosed
US-20250381117-A1 COSMETIC COMPOSITION COMPRISING CAFFEINE AND MELATONIN MARY KAY INC. (US) 2025-12-18 US disclosed
EP-0052341-B1 OROTIC ACID DERIVATIVES AND THEIR USE AS AGRICULTURAL CHEMICALS UBE INDUSTRIES, LTD. (JP) 1985-05-29 EP disclosed
US-4480110-A FROM SUBSTITUTED UREAS AND ALCOHOL BAYER AKTIENGESELLSCHAFT (DE) 1984-10-30 US disclosed
US-4444863-A UREA COMPOUND FUJI PHOTO FILM CO., LTD. (JP) 1984-04-24 US disclosed
US-4400508-A AGRICULTURE; PLANT DISEASES; ANTISEPTICS UBE INDUSTRIES, LTD. (JP) 1983-08-23 US disclosed
US-4399280-A MOTHPROOFING, PROTECTION OF KERATINOUS MATERIAL CIBA-GEIGY CORPORATION (US) 1983-08-16 US disclosed
EP-0052341-A1 Orotic acid derivatives and their use as agricultural chemicals UBE INDUSTRIES, LTD. (JP) 1982-05-26 EP disclosed
US-4283444-A MOTHPROOFING WOOLS, FURS, SKINS CIBA-GEIGY CORPORATION (US) 1981-08-11 US disclosed
US-4275215-A QUATERNARY AMMONIUM OR PHOSPHONIUM SALTS CATALYZE REACTION OF HYPOHALITE AND A DIPHENYL UREA DOW CHEMICAL COMPANY LIMITED (GB) 1981-06-23 US disclosed
EP-0004733-A2 Diaryl substituted pyrazoline carboxanilides, processes for preparing them, insecticidal compositions and uses thereof, and intermediates therefor IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1979-10-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260090980-A1 COSMETIC COMPOSITIONS AND METHODS OF USING THE SAME CUTA, DSG1, HIRA MEN1 901/4885KMT2A 2972/4885ALDH1A1 3767/4885
US-20250387310-A1 COMPOSITIONS THAT ENHANCE THE COOLING EFFECT TAS2R30, TAS2R1, TAS2R20 MEN1 2514/4885KMT2A 2006/4885ALDH1A1 540/4885
US-20260083659-A1 SUNSCREEN COMPOSITIONS AND METHODS OF USE CUTA, TYR, SUN2 MEN1 4259/4885KMT2A 3464/4885ALDH1A1 327/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.