SCHEMBL18902816

SCHEMBL18902816

C1=CCCC(c2cc(-c3ccccc3)cc(-c3ccc4c(-c5ccc(-c6ccccn6)cc5)c5ccccc5c(-c5ccc(-c6ccccn6)cc5)c4c3)c2)=C1

nearest known ligand 0.34

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
DHODH Q02127 1/20 0.34
NPY5R Q15761 1/20 0.32
TSHR P16473 2/20 0.31
HSD17B10 Q99714 2/20 0.31
MAPK1 P28482 1/20 0.31
KDM4E B2RXH2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
TP53 P04637 1/20 0.30
MAPT P10636 1/20 0.30
PKM P14618 1/20 0.30
HPGD P15428 1/20 0.30
RAB9A P51151 1/20 0.30
KLF5 Q13887 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PRMT5 O14744 2/20 0.30
WDR77 Q9BQA1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22699419 0.85
SCHEMBL17877066 0.84 DHODH (0.45) DHODHTSHRHSD17B10MAPK1KDM4E
SCHEMBL25700517 0.84 DHODH (0.45) DHODHTSHRHSD17B10MAPK1KDM4E
SCHEMBL10030048 0.84 DHODH (0.45) DHODHTSHRHSD17B10MAPK1KDM4E
SCHEMBL23640992 0.82 RAB9A (0.38) DHODHNPY5RTSHRHSD17B10MAPK1
SCHEMBL24029205 0.82 DHODH (0.37) DHODHNPY5RTSHRHSD17B10MAPK1
SCHEMBL10030034 0.81 DHODH (0.45) DHODHTSHRHSD17B10MAPK1KDM4E
SCHEMBL10300965 0.81 DHODH (0.47) DHODHNPY5RTSHRHSD17B10MAPK1
SCHEMBL24565242 0.81 DHODH (0.47) DHODHNPY5RTSHRHSD17B10MAPK1
SCHEMBL10030023 0.81 DHODH (0.47) DHODHNPY5RTSHRHSD17B10MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3822258-B1 CONDENSED CYCLIC COMPOUND, COMPOSITION INCLUDING THE SAME, AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THIN FILM FORMED FROM THE COMPOSITION SAMSUNG DISPLAY CO LTD (KR) 2022-06-15 EP disclosed
EP-3930017-A1 ORGANIC LIGHT-EMITTING DEVICE AND APPARATUS INCLUDING THE SAME Samsung Display Co., Ltd. (KR) 2021-12-29 EP disclosed
EP-3188268-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-07-05 EP disclosed
EP-3174121-A1 ORGANIC LIGHT-EMITTING DEVICE Samsung Display Co., Ltd. (KR) 2017-05-31 EP disclosed