Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOAT1 | P35610 | 1/20 | 0.42 |
| ▸ | PLA2G2A | P14555 | 5/20 | 0.39 |
| ▸ | PLA2G10 | O15496 | 3/20 | 0.39 |
| ▸ | PLA2G1B | P04054 | 2/20 | 0.39 |
| ▸ | PLA2G5 | P39877 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10123593 | 0.78 | POLB (0.49) | POLBL3MBTL1GPR84HSD11B1MEN1 | |
| Biphenyl SCHEMBL2984118 | 0.77 | LTA4H (0.50) | SOAT1MEN1CYP3A4KMT2A | |
| Biphenyl SCHEMBL15361529 | 0.77 | LTA4H (0.50) | SOAT1MEN1CYP3A4KMT2A | |
| Biphenyl SCHEMBL15361699 | 0.77 | LTA4H (0.50) | SOAT1MEN1CYP3A4KMT2A | |
| Biphenyl SCHEMBL2991687 | 0.77 | LTA4H (0.50) | SOAT1MEN1CYP3A4KMT2A | |
| Biphenyl SCHEMBL1263228 | 0.77 | LTA4H (0.50) | SOAT1MEN1CYP3A4KMT2A | |
| Biphenyl SCHEMBL2989570 | 0.77 | LTA4H (0.50) | SOAT1MEN1CYP3A4KMT2A | |
| Biphenyl SCHEMBL7863473 | 0.77 | LTA4H (0.50) | SOAT1MEN1CYP3A4KMT2A | |
| Biphenyl SCHEMBL2848356 | 0.77 | LTA4H (0.50) | SOAT1MEN1CYP3A4KMT2A | |
| Biphenyl SCHEMBL15361572 | 0.77 | LTA4H (0.50) | SOAT1MEN1CYP3A4KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3173408-A1 | PHENYL TETRAHYDROISOQUINOLINE COMPOUND SUBSTITUTED WITH HETEROARYL | Taisho Pharmaceutical Co., Ltd. (JP) | 2017-05-31 | — | — | EP | disclosed |