Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.33 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.33 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | CA9 | Q16790 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.31 |
| ▸ | ACE | P12821 | 1/20 | 0.30 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.30 |
| ▸ | DNM1 | Q05193 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18902725 | 0.93 | KMT2A (0.39) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL15445157 | 0.84 | CA1 (0.39) | KMT2AHDAC3HDAC1HDAC2HDAC10 | |
| SCHEMBL13499932 | 0.80 | KMT2A (0.31) | KMT2ACXCR4 | |
| SCHEMBL18902929 | 0.80 | KMT2A (0.31) | KMT2ACXCR4 | |
| SCHEMBL16330387 | 0.75 | HDAC3 (0.40) | HDAC3HDAC1HDAC2HDAC10HDAC11 | |
| SCHEMBL9452819 | 0.75 | RAD52 (0.37) | KMT2ACXCR4 | |
| SCHEMBL9417398 | 0.75 | RAD52 (0.37) | KMT2ACXCR4 | |
| SCHEMBL9452852 | 0.75 | RAD52 (0.37) | KMT2ACXCR4 | |
| SCHEMBL22009542 | 0.75 | RAD52 (0.37) | KMT2ACXCR4 | |
| SCHEMBL9452856 | 0.75 | RAD52 (0.37) | KMT2ACXCR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725572-B1 | MACROMOLECULAR NUCLEOTIDE COMPOUNDS AND METHODS FOR USING THE SAME | AGCT GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |