Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA9 | Q16790 | 2/20 | 0.39 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 7/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 7/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 7/20 | 0.36 |
| ▸ | HDAC7 | Q8WUI4 | 7/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 7/20 | 0.36 |
| ▸ | HDAC10 | Q969S8 | 7/20 | 0.36 |
| ▸ | HDAC11 | Q96DB2 | 7/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 7/20 | 0.36 |
| ▸ | HDAC6 | Q9UBN7 | 7/20 | 0.36 |
| ▸ | HDAC9 | Q9UKV0 | 7/20 | 0.36 |
| ▸ | HDAC5 | Q9UQL6 | 7/20 | 0.36 |
| ▸ | KDM4A | O75164 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | TET2 | Q6N021 | 1/20 | 0.34 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16330387 | 0.85 | HDAC3 (0.40) | CA1CA2CA9DNM1HDAC3 | |
| SCHEMBL16330596 | 0.85 | DNM1 (0.37) | CA1CA2CA9DNM1KDM4A | |
| SCHEMBL22732475 | 0.85 | DNM1 (0.37) | CA1CA2CA9DNM1KDM4A | |
| SCHEMBL18902885 | 0.84 | KMT2A (0.35) | CA1CA2CA9DNM1HDAC3 | |
| SCHEMBL13033284 | 0.81 | CASP2 (0.48) | DNM1HDAC3HDAC1HDAC2HDAC8 | |
| SCHEMBL2055305 | 0.81 | DNM1 (0.39) | CA1CA2CA9DNM1KDM4A | |
| SCHEMBL14576169 | 0.81 | PHF8 (0.42) | DNM1HDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL12290350 | 0.80 | ALDH1A1 (0.38) | CA1CA2DNM1KDM4AHIF1A | |
| SCHEMBL8431925 | 0.80 | — | — | |
| SCHEMBL9921469 | 0.79 | CASP2 (0.46) | DNM1HDAC3HDAC1HDAC2HDAC8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1725572-B1 | MACROMOLECULAR NUCLEOTIDE COMPOUNDS AND METHODS FOR USING THE SAME | AGCT GMBH (DE) | 2017-05-31 | — | — | EP | disclosed |
| US-9035035-B2 | Macromolecular nucleotide compounds and methods for using the same | GENOVOXX GMBH (DE) | 2015-05-19 | — | — | US | disclosed |
| US-8637650-B2 | Macromolecular nucleotide compounds and methods for using the same | GENOVOXX GMBH (DE) | 2014-01-28 | — | — | US | disclosed |