Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BRD4 | O60885 | 5/20 | 0.32 |
| ▸ | BRD2 | P25440 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4554973 | 0.72 | — | — | |
| SCHEMBL18884406 | 0.70 | — | — | |
| SCHEMBL20016686 | 0.70 | — | — | |
| SCHEMBL27551772 | 0.70 | ROCK1 (0.31) | — | |
| SCHEMBL3599701 | 0.70 | BRD4 (0.46) | KMT2ABRD4BRD2ALDH1A1L3MBTL1 | |
| SCHEMBL1758424 | 0.70 | BRD4 (0.38) | KMT2ABRD4BRD2ALDH1A1L3MBTL1 | |
| SCHEMBL8260822 | 0.68 | RIPK1 (0.44) | KMT2ABRD4BRD2ALDH1A1L3MBTL1 | |
| SCHEMBL18904135 | 0.67 | BRD4 (0.33) | KMT2ABRD4BRD2ALDH1A1L3MBTL1 | |
| SCHEMBL2191777 | 0.67 | BRD4 (0.42) | KMT2ABRD4BRD2ALDH1A1L3MBTL1 | |
| SCHEMBL27424284 | 0.67 | NPC1 (0.31) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |
| CN-1193963-A | Aromatic compounds and pharmaceutical compositions containing them | ZENECA LTD (GB) | 1998-09-23 | — | — | CN | disclosed |