Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NMT1 | P30419 | 8/20 | 0.45 |
| ▸ | EP300 | Q09472 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | BCDIN3D | Q7Z5W3 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18904119 | 0.81 | NMT1 (0.44) | NMT1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16502968 | 0.79 | NMT1 (0.42) | NMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL18903961 | 0.79 | NMT1 (0.52) | NMT1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL16509630 | 0.78 | NMT1 (0.74) | NMT1LMNAHTTSMN1; SMN2 | |
| SCHEMBL18903984 | 0.78 | NMT1 (0.52) | NMT1 | |
| SCHEMBL16503019 | 0.77 | NMT1 (0.41) | NMT1LMNAALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL18903967 | 0.77 | NMT1 (0.53) | NMT1LMNA | |
| SCHEMBL16503018 | 0.75 | ATP1A1 (0.35) | NMT1ALDH1A1 | |
| SCHEMBL18903819 | 0.75 | NMT1 (0.37) | NMT1 | |
| SCHEMBL18904009 | 0.73 | NMT1 (0.46) | NMT1LMNAHTTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2980076-B1 | Pyrazolyl derivatives | UNIV DUNDEE (GB) | 2017-05-31 | — | — | EP | disclosed |