SCHEMBL18904475

SCHEMBL18904475

c1cnc2c(c1)ccc1ccc(-c3ccc4c(c3)-c3ccc(-c5ccc6c7ccccc7c7ccccc7c6c5)c5cccc-4c35)nc12

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ CCR1 P32246 4/20 0.36
▸ CCR8 P51685 4/20 0.36
▸ TSHR P16473 3/20 0.36
▸ LMNA P02545 3/20 0.36
▸ HIF1A Q16665 2/20 0.36
▸ CCR5 P51681 2/20 0.36
▸ KDM4E B2RXH2 2/20 0.36
▸ MAPT P10636 2/20 0.36
▸ ALOX15 P16050 2/20 0.36
▸ HTT P42858 2/20 0.36
▸ SMN1; SMN2 Q16637 2/20 0.36
▸ TDP1 Q9NUW8 2/20 0.36
▸ GMNN O75496 1/20 0.36
▸ TP53 P04637 1/20 0.36
▸ HSP90AA1 P07900 1/20 0.36
▸ MMP2 P08253 1/20 0.36
▸ CYP3A4 P08684 1/20 0.36
▸ CYP2D6 P10635 1/20 0.36
▸ MMP9 P14780 1/20 0.36
▸ NFKB1 P19838 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17899288 0.89 BRD4 (0.43) CCR1CCR8TSHRLMNAHIF1A
SCHEMBL17899284 0.88 BRD4 (0.42) CCR1CCR8TSHRLMNAHIF1A
SCHEMBL18904485 0.88 CCR1 (0.42) CCR1CCR8TSHRLMNAHIF1A
SCHEMBL11992174 0.87 BRD4 (0.41) CCR1CCR8TSHRLMNAHIF1A
SCHEMBL17899291 0.87 LMNA (0.43) CCR1CCR8TSHRLMNAHIF1A
SCHEMBL17899296 0.86 CCR1 (0.38) CCR1CCR8TSHRLMNAHIF1A
SCHEMBL11992173 0.86 TSHR (0.40) CCR1CCR8TSHRLMNAHIF1A
SCHEMBL18904492 0.86 CCR1 (0.40) CCR1CCR8TSHRLMNAHIF1A
SCHEMBL18904462 0.86 TOP1 (0.43) CCR1CCR8TSHRLMNAHIF1A
SCHEMBL18886531 0.85 CCR1 (0.50) CCR1CCR8TSHRLMNAHIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10177317-B2 Organic light emitting display device LG DISPLAY CO., LTD. (KR) 2019-01-08 — — US disclosed
US-20170155055-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2017-06-01 — — US disclosed
US-20170155055-A1 ORGANIC LIGHT EMITTING DISPLAY DEVICE LG DISPLAY CO., LTD. (KR) 2017-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10177317-B2 Organic light emitting display device OCIAD2, L1CAM, OCIAD1 CCR1 3050/4885CCR8 2243/4885TSHR 4428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback