Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 5/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 5/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 5/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.37 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | HRH1 | P35367 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18905316 | 0.98 | KEAP1 (0.41) | KEAP1NFE2L2ATML3MBTL1CYP2D6 | |
| SCHEMBL18905434 | 0.84 | CYP19A1 (0.35) | KEAP1NFE2L2ATML3MBTL1CYP2D6 | |
| SCHEMBL19130799 | 0.83 | NPC1 (0.42) | KEAP1NFE2L2CYP2D6CHRM2CHRM1 | |
| SCHEMBL18911003 | 0.83 | NPC1 (0.42) | KEAP1NFE2L2CYP2D6CHRM2CHRM1 | |
| SCHEMBL9906166 | 0.82 | KEAP1 (0.56) | KEAP1NFE2L2ATML3MBTL1CYP2D6 | |
| SCHEMBL18415154 | 0.82 | KEAP1 (0.56) | KEAP1NFE2L2ATML3MBTL1CYP2D6 | |
| SCHEMBL13429177 | 0.82 | KEAP1 (0.56) | KEAP1NFE2L2ATML3MBTL1CYP2D6 | |
| SCHEMBL13131231 | 0.82 | KEAP1 (0.56) | KEAP1NFE2L2ATML3MBTL1CYP2D6 | |
| SCHEMBL18905379 | 0.82 | KEAP1 (0.35) | KEAP1NFE2L2ATML3MBTL1CYP2D6 | |
| SCHEMBL14376208 | 0.81 | CYP19A1 (0.42) | KEAP1NFE2L2CYP2D6CHRM2CHRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170154766-A1 | SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-01 | — | — | US | disclosed |