Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.44 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.44 |
| ▸ | PTGS1 | P23219 | 8/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.35 |
| ▸ | NR1I2 | O75469 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.33 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19159318 | 0.79 | ESR1 (0.45) | ESR1ESR2PTGS1MEN1LMNA | |
| SCHEMBL10581272 | 0.79 | ESR1 (0.67) | ESR1ESR2PTGS1PTGS2NR1I2 | |
| SCHEMBL6264609 | 0.79 | ESR1 (0.67) | ESR1ESR2PTGS1PTGS2NR1I2 | |
| SCHEMBL14553634 | 0.78 | HTT (0.45) | ESR1ESR2PTGS1MEN1LMNA | |
| SCHEMBL23145325 | 0.77 | HTT (0.44) | ESR1ESR2PTGS1LMNACYP1A2 | |
| SCHEMBL2082470 | 0.77 | ESR1 (0.44) | ESR1ESR2PTGS1PTGS2MEN1 | |
| SCHEMBL23145323 | 0.77 | HTT (0.44) | ESR1ESR2PTGS1LMNACYP1A2 | |
| SCHEMBL14553635 | 0.77 | ALDH1A1 (0.50) | ESR1ESR2PTGS1TP53CYP2C9 | |
| SCHEMBL23145395 | 0.77 | HTT (0.44) | ESR1ESR2PTGS1LMNACYP1A2 | |
| SCHEMBL2082467 | 0.77 | ESR1 (0.44) | ESR1ESR2PTGS1PTGS2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170154766-A1 | SILICON-CONTAINING CONDENSATE, COMPOSITION FOR FORMING A SILICON-CONTAINING RESIST UNDER LAYER FILM, AND PATTERNING PROCESS | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2017-06-01 | — | — | US | disclosed |