SCHEMBL18906154

SCHEMBL18906154

C=C(C)C(=O)OCCOC(=O)c1cccc2c(O)c(O)ccc12

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.40
KDM4A O75164 1/20 0.40
KDM4C Q9H3R0 1/20 0.40
TSHR P16473 5/20 0.40
TDP1 Q9NUW8 3/20 0.39
ALDH1A1 P00352 2/20 0.38
THRB P10828 1/20 0.38
L3MBTL1 Q9Y468 2/20 0.36
HRH3 Q9Y5N1 1/20 0.36
SERPINE1 P05121 1/20 0.36
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CDC25B P30305 1/20 0.36
TP53 P04637 1/20 0.35
CYP3A4 P08684 1/20 0.35
MAPK1 P28482 1/20 0.35
POLB P06746 3/20 0.35
GAA P10253 1/20 0.35
KMT2A Q03164 1/20 0.35
APEX1 P27695 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18904507 0.90 CDC25B (0.36) KDM4EKDM4AKDM4CTSHRTDP1
SCHEMBL10040387 0.88 CDC25B (0.46) KDM4EKDM4AKDM4CTSHRTDP1
SCHEMBL10064079 0.85 KDM4E (0.45) KDM4EKDM4AKDM4CTSHRTDP1
SCHEMBL14001888 0.85 TSHR (0.45) KDM4EKDM4AKDM4CTSHRTDP1
SCHEMBL26312591 0.84 TSHR (0.47) KDM4ETSHRTDP1ALDH1A1THRB
SCHEMBL14001887 0.83 TSHR (0.43) KDM4ETSHRTDP1ALDH1A1THRB
SCHEMBL5030862 0.81 HRH3 (0.53) KDM4ETSHRTDP1ALDH1A1L3MBTL1
SCHEMBL961274 0.79 TDP1 (0.63) TSHRTDP1ALDH1A1THRBL3MBTL1
SCHEMBL29277031 0.79 TDP1 (0.56) KDM4ETSHRTDP1ALDH1A1L3MBTL1
SCHEMBL129437 0.79 TSHR (0.62) TSHRTDP1ALDH1A1THRBL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170153547-A1 COATING COMPOSITIONS FOR USE WITH AN OVERCOATED PHOTORESIST DUPONT SPECIALTY MATERIALS KOREA LTD (KR) 2017-06-01 US disclosed