Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLP1R | P43220 | 8/20 | 0.49 |
| ▸ | CA1 | P00915 | 4/20 | 0.40 |
| ▸ | CA2 | P00918 | 4/20 | 0.40 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.38 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.36 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.36 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.35 |
| ▸ | TLR2 | O60603 | 1/20 | 0.34 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18906902 | 1.00 | GLP1R (0.49) | GLP1RCA1CA2SIRT6SIRT1 | |
| SCHEMBL23995632 | 0.99 | GLP1R (0.50) | GLP1RCA1CA2SIRT6SIRT1 | |
| SCHEMBL18911933 | 0.88 | GLP1R (0.45) | GLP1RCA1CA2CTSSCTSK | |
| SCHEMBL18912601 | 0.88 | GLP1R (0.41) | GLP1RCA1CA2SIRT6SIRT1 | |
| SCHEMBL13699550 | 0.84 | GLP1R (0.54) | GLP1RCA1CA2CTSSCTSK | |
| SCHEMBL13699549 | 0.84 | GLP1R (0.56) | GLP1RCA1CA2CTSSCTSK | |
| SCHEMBL3485167 | 0.83 | GLP1R (0.51) | GLP1RCA1CA2ADORA1 | |
| SCHEMBL3486505 | 0.83 | GLP1R (0.51) | GLP1RCA1CA2ADORA1 | |
| SCHEMBL4517738 | 0.83 | GLP1R (0.54) | GLP1RSIRT6SIRT1TLR2 | |
| SCHEMBL3484885 | 0.83 | GLP1R (0.54) | GLP1RSIRT6SIRT1TLR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017089890-A1 | CONJUGATES COMPRISING SELF-IMMOLATIVE GROUPS AND METHODS RELATED THERETO | LEGOCHEM BIOSCIENCES, INC. (KR) | 2017-06-01 | — | — | WO | disclosed |