SCHEMBL18911933

SCHEMBL18911933

CC(C)(C)OC(=O)NOCCOCCOCCNC(=O)[C@H](CCCCNC(=O)COCCOCCN=[N+]=[N-])NC(=O)COCCOCCN=[N+]=[N-]

nearest known ligand 0.45

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
▸ GLP1R P43220 8/20 0.45
▸ CA1 P00915 5/20 0.37
▸ CA2 P00918 5/20 0.37
▸ CTSS P25774 1/20 0.33
▸ CTSK P43235 1/20 0.33
▸ CAPN1 P07384 1/20 0.33
▸ ADORA1 P30542 1/20 0.33
▸ F10 P00742 1/20 0.32
▸ CTSL P07711 1/20 0.32
▸ CTSB P07858 1/20 0.32
▸ SIRT5 Q9NXA8 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18911532 0.92 GLP1R (0.39) GLP1RCA1CA2
SCHEMBL18911535 0.91 GLP1R (0.42) GLP1RCA1CA2CTSSCTSK
SCHEMBL18906906 0.88 GLP1R (0.49) GLP1RCA1CA2CTSSCTSK
SCHEMBL18906902 0.88 GLP1R (0.49) GLP1RCA1CA2CTSSCTSK
SCHEMBL23995632 0.87 GLP1R (0.50) GLP1RCA1CA2CTSSCTSK
SCHEMBL21018605 0.85 GLP1R (0.44) GLP1RCA1CA2F10CTSL
SCHEMBL3485145 0.84 GLP1R (0.50) GLP1RCTSLCTSB
SCHEMBL3485150 0.84 GLP1R (0.50) GLP1RCTSLCTSB
SCHEMBL3485821 0.84 GLP1R (0.50) GLP1RCTSLCTSB
SCHEMBL18088370 0.84 CA1 (0.44) GLP1RCA1CA2CTSSCTSK

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220218840-A1 ANTIBODY-DRUG CONJUGATES COMPRISING BRANCHED LINKERS AND METHODS RELATED THERETO LIGACHEM BIOSCIENCES INC. (KR) 2022-07-14 — — US disclosed
US-11173214-B2 Antibody-drug conjugates comprising branched linkers and methods related thereto LEGOCHEM BIOSCIENCES, INC. (KR) 2021-11-16 — — US disclosed
US-11167040-B2 Conjugates comprising peptide groups and methods related thereto LEGOCHEM BIOSCIENCES, INC. (KR) 2021-11-09 — — US disclosed
US-20200297865-A1 CONJUGATES COMPRISING SELF-IMMOLATIVE GROUPS AND METHODS RELATED THERETO LIGACHEM BIOSCIENCES INC. (KR) 2020-09-24 — — US disclosed
US-20190151465-A1 ANTIBODY-DRUG CONJUGATES COMPRISING BRANCHED LINKERS AND METHODS RELATED THERETO LIGACHEM BIOSCIENCES INC. (KR) 2019-05-23 — — US disclosed
WO-2017089895-A1 ANTIBODY-DRUG CONJUGATES COMPRISING BRANCHED LINKERS AND METHODS RELATED THERETO LEGOCHEM BIOSCIENCES, INC. (KR) 2017-06-01 — — WO disclosed
WO-2017089894-A1 CONJUGATES COMPRISING PEPTIDE GROUPS AND METHODS RELATED THERETO LEGOCHEM BIOSCIENCES, INC. (KR) 2017-06-01 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190151465-A1 ANTIBODY-DRUG CONJUGATES COMPRISING BRANCHED LINKERS AND METHODS RELATED THERETO PA2G4, FCGRT, CLTB GLP1R 1694/4885CA1 569/4885CA2 2471/4885
US-11167040-B2 Conjugates comprising peptide groups and methods related thereto DAO, LPO, TYRO3 GLP1R 129/4885CA1 106/4885CA2 807/4885
US-11173214-B2 Antibody-drug conjugates comprising branched linkers and methods related thereto PA2G4, FCGRT, CLTB GLP1R 1694/4885CA1 569/4885CA2 2471/4885
US-20200297865-A1 CONJUGATES COMPRISING SELF-IMMOLATIVE GROUPS AND METHODS RELATED THERETO LPO, NOXO1, DAO GLP1R 1774/4885CA1 222/4885CA2 1164/4885
US-20220218840-A1 ANTIBODY-DRUG CONJUGATES COMPRISING BRANCHED LINKERS AND METHODS RELATED THERETO PA2G4, FCGRT, CLTB GLP1R 1694/4885CA1 569/4885CA2 2471/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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