Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.35 |
| ▸ | FAAH | O00519 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22992245 | 1.00 | DPP4 (0.35) | DPP4FAAHBCHEACHE | |
| SCHEMBL23219678 | 0.86 | DPP4 (0.33) | DPP4FAAHBCHEACHE | |
| SCHEMBL27415161 | 0.81 | CA12 (0.33) | DPP4 | |
| SCHEMBL18098236 | 0.79 | LMNA (0.40) | DPP4 | |
| SCHEMBL14669 | 0.79 | — | — | |
| SCHEMBL29889501 | 0.78 | DPP4 (0.34) | DPP4 | |
| SCHEMBL2172067 | 0.77 | — | — | |
| SCHEMBL8420354 | 0.77 | — | — | |
| SCHEMBL21177575 | 0.77 | — | — | |
| SCHEMBL22992244 | 0.76 | DPP4 (0.36) | DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091617-A1 | TRIAZOLE ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |