Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | CRHBP | P24387 | 1/20 | 0.41 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | LCK | P06239 | 1/20 | 0.36 |
| ▸ | PPARD | Q03181 | 1/20 | 0.36 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7641684 | 0.92 | TDP1 (0.51) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL6080172 | 0.92 | TDP1 (0.51) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL6080202 | 0.92 | TDP1 (0.51) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL11500452 | 0.92 | TDP1 (0.51) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL14580010 | 0.90 | TDP1 (0.53) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7058682 | 0.87 | TDP1 (0.44) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL1342413 | 0.85 | GPR84 (0.53) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL7744050 | 0.85 | GPR84 (0.53) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL1653785 | 0.85 | GPR84 (0.53) | TDP1MEN1KMT2AL3MBTL1MAPT | |
| SCHEMBL8979832 | 0.85 | GPR84 (0.53) | TDP1MEN1KMT2AL3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011061609-A2 | PROCESSES FOR THE PREPARATION OF CILASTATIN | RANBAXY LABORATORIES LIMITED (IN) | 2011-05-26 | — | — | WO | claimed |
| WO-2011061609-A2 | PROCESSES FOR THE PREPARATION OF CILASTATIN | RANBAXY LABORATORIES LIMITED (IN) | 2011-05-26 | — | — | WO | disclosed |