Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.45 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.45 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 2/20 | 0.43 |
| ▸ | CA7 | P43166 | 2/20 | 0.43 |
| ▸ | CA9 | Q16790 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | CASP1 | P29466 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.43 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16098960 | 0.79 | SMN1; SMN2 (0.44) | SMN1; SMN2GSK3BALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL21261434 | 0.76 | MAPT (0.55) | SMN1; SMN2GSK3BALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL10602199 | 0.76 | GSK3B (0.48) | SMN1; SMN2GSK3BALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL2144205 | 0.74 | GSK3B (0.46) | SMN1; SMN2GSK3BALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29155422 | 0.74 | CA1 (0.46) | SMN1; SMN2GSK3BALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL30683788 | 0.74 | CA1 (0.46) | SMN1; SMN2GSK3BALDH1A1HSP90AA1HSP90AB1 | |
| SCHEMBL13401678 | 0.73 | — | — | |
| SCHEMBL29695445 | 0.72 | TNKS (0.48) | SMN1; SMN2GSK3BALDH1A1KDM4EHSD17B10 | |
| SCHEMBL15914816 | 0.72 | TNKS (0.48) | SMN1; SMN2GSK3BALDH1A1KDM4EHSD17B10 | |
| SCHEMBL21261611 | 0.71 | MAPT (0.50) | SMN1; SMN2KDM4EPDK2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9079877-B2 | Process for preparing chiral compounds | PFIZER INC. (US) | 2015-07-14 | — | — | US | disclosed |
| EP-2185713-B1 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | PFIZER PROD INC (US) | 2014-09-10 | — | — | EP | disclosed |
| EP-2532660-B1 | Process for preparing chiral compounds | PFIZER PROD INC (US) | 2014-09-10 | — | — | EP | disclosed |
| US-20140187794-A1 | Process for Preparing Chiral Compounds | PFIZER INC. (US) | 2014-07-03 | — | — | US | disclosed |
| US-20140065407-A1 | MANUFACTURE OF LITHOGRAPHIC PRINTING PLATE PRECURSORS FOR ABLATION IMAGING | KODAK REALTY INC. | 2014-03-06 | — | — | US | disclosed |
| US-8642783-B2 | Process for preparing chiral compounds | PFIZER INC. (US) | 2014-02-04 | — | — | US | disclosed |
| EP-2205551-B1 | METHOD OF PRODUCING AMINO DIALKOXY ALDEHYDES VIA HYDROFORMYLATION | REDDY S LAB EU LTD DR (GB) | 2014-01-08 | — | — | EP | disclosed |
| EP-2532660-A1 | Synthetic intermediates prepared using a 2-deoxyribose-5-phosphate aldolase (DERA) chemoenzymatic process | Pfizer Products Inc. (US) | 2012-12-12 | — | — | EP | disclosed |
| WO-2012106169-A1 | METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATES | EASTMAN KODAK COMPANY (US) | 2012-08-09 | — | — | WO | disclosed |
| US-20120192741-A1 | METHOD FOR PREPARING LITHOGRAPHIC PRINTING PLATES | NPEC INC. | 2012-08-02 | — | — | US | disclosed |
| WO-2012099833-A1 | PREPARING LITHOGRAPHIC PRINTING PLATES BY ABLATION IMAGING | EASTMAN KODAK COMPANY (US) | 2012-07-26 | — | — | WO | disclosed |
| US-20120189770-A1 | PREPARING LITHOGRAPHIC PRINTING PLATES BY ABLATION IMAGING | KODAK REALTY INC. | 2012-07-26 | — | — | US | disclosed |
| US-20110118476-A1 | Process for Preparing Chiral Compounds | PFIZER INC. | 2011-05-19 | — | — | US | disclosed |
| EP-2205551-A1 | METHOD OF PRODUCING AMINO DIALKOXY ALDEHYDES VIA HYDROFORMYLATION | DR REDDY'S LABORATORIES (EU) LIMITED (GB) | 2010-07-14 | — | — | EP | disclosed |
| EP-2185713-A2 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | Pfizer Products Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009019561-A2 | PROCESS FOR PREPARING CHIRAL COMPOUNDS | PFIZER PRODUCTS INC. (US) | 2009-02-12 | — | — | WO | disclosed |
| WO-2008134327-A1 | METHOD OF PRODUCING AMINO DIALKOXY ALDEHYDES VIA HYDROFORMYLATION | DOW GLOBAL TECHNOLOGIES INC. (US) | 2008-11-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140187794-A1 | Process for Preparing Chiral Compounds | DERA, ALDOA, DPYD | SMN1; SMN2 3910/4885GSK3B 472/4885ALDH1A1 76/4885 |
| US-20110118476-A1 | Process for Preparing Chiral Compounds | DERA, ALDOA, DPYD | SMN1; SMN2 3910/4885GSK3B 472/4885ALDH1A1 76/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.