SCHEMBL10602199

SCHEMBL10602199

O=C1NC(Cl)(Cl)c2ccccc21

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GSK3B P49841 1/20 0.48
S100A4 P26447 1/20 0.47
ALDH1A1 P00352 5/20 0.46
KDM4E B2RXH2 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ITGA4 P13612 1/20 0.44
CACNB4 O00305 1/20 0.42
CACNA1A O00555 1/20 0.42
CACNA1G O43497 1/20 0.42
CACNG3 O60359 1/20 0.42
CACNA1F O60840 1/20 0.42
CACNA1H O95180 1/20 0.42
CACNB3 P54284 1/20 0.42
CACNA2D1 P54289 1/20 0.42
CACNG7 P62955 1/20 0.42
CACNA1B Q00975 1/20 0.42
CACNA1D Q01668 1/20 0.42
CACNB1 Q02641 1/20 0.42
CACNG1 Q06432 1/20 0.42
CACNB2 Q08289 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1890817 0.76 SMN1; SMN2 (0.47) GSK3BS100A4ALDH1A1KDM4EHSD17B10
SCHEMBL2144205 0.76 GSK3B (0.46) GSK3BS100A4ALDH1A1KDM4EHSD17B10
SCHEMBL23836741 0.75 GSK3B (0.41) GSK3BS100A4ALDH1A1KDM4EHSD17B10
SCHEMBL4915582 0.75 CFTR (0.43) GSK3BS100A4ALDH1A1KDM4EHSD17B10
SCHEMBL29695445 0.74 TNKS (0.48) GSK3BS100A4ALDH1A1KDM4EHSD17B10
SCHEMBL15914816 0.74 TNKS (0.48) GSK3BS100A4ALDH1A1KDM4EHSD17B10
SCHEMBL16098960 0.72 SMN1; SMN2 (0.44) GSK3BS100A4ALDH1A1KDM4EHSD17B10
SCHEMBL11990851 0.72 ITGA4 (0.48) GSK3BS100A4ALDH1A1KDM4EHSD17B10
SCHEMBL10602710 0.72 ALDH1A1 (0.43) GSK3BS100A4ALDH1A1KDM4EHSD17B10
SCHEMBL31375636 0.71 ALDH1A1 (0.43) GSK3BS100A4ALDH1A1KDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-58015557-A None JP disclosed
EP-0150711-B1 AZO-PIGMENTS AND PROCESS FOR THEIR PREPARATION DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1989-12-13 EP disclosed
EP-0211272-A2 AZO compound and colored composition containing same DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1987-02-25 EP disclosed
US-4638052-A WEATHERPROOFING, COLORFASTNESS DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1987-01-20 US disclosed
EP-0150711-A2 Azo-pigments and process for their preparation DAINICHISEIKA COLOR & CHEMICALS MFG. CO. LTD. (JP) 1985-08-07 EP disclosed
JP-S5815557-A AZOMETHINE PIGMENT DAINICHI SEIKA KOGYO KK 1983-01-28 JP disclosed
US-4221709-A Azo pigments DAINICHISEIKA COLOR & CHEMICALS MFG. CO., LTD. (JP) 1980-09-09 US disclosed