Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | GFER | P55789 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 3/20 | 0.36 |
| ▸ | BRD4 | O60885 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 5/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.34 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31616888 | 0.89 | ALDH1A1 (0.35) | ALDH1A1GFERDRD2BRD4SMN1; SMN2 | |
| SCHEMBL1007078 | 0.86 | ALDH1A1 (0.37) | ALDH1A1GFERDRD2BRD4TDP1 | |
| SCHEMBL29544458 | 0.80 | GAA (0.40) | ALDH1A1GFERDRD2BRD4SMN1; SMN2 | |
| SCHEMBL8296901 | 0.78 | KMT2A (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ACNR1 | |
| SCHEMBL1079551 | 0.78 | GAA (0.50) | ALDH1A1SMN1; SMN2TDP1GAALMNA | |
| SCHEMBL5163133 | 0.77 | ALDH1A1 (0.38) | ALDH1A1GFERDRD2BRD4SMN1; SMN2 | |
| SCHEMBL20399777 | 0.76 | BRD4 (0.41) | ALDH1A1GFERDRD2BRD4MEN1 | |
| SCHEMBL18665224 | 0.76 | CA12 (0.43) | ALDH1A1GFERDRD2BRD4TDP1 | |
| SCHEMBL8253700 | 0.75 | MEN1 (0.42) | ALDH1A1SMN1; SMN2MEN1KMT2ACNR1 | |
| SCHEMBL27244243 | 0.74 | SMN1; SMN2 (0.37) | ALDH1A1SMN1; SMN2MEN1KMT2APKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-05-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110118236-A1 | HETEROCYCLIC COMPOUND | GRIN1, GRM1, GRIK1 | ALDH1A1 614/4885GFER 1046/4885DRD2 510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.