SCHEMBL1890837

SCHEMBL1890837

CCCCc1c(CC)ccc(CC)c1-c1c(-c2c(CC)ccc(CC)c2CCCC)c(-c2c(CC)ccc(CC)c2CCCC)c2c(c1-c1c(CC)ccc(CC)c1CCCC)=c1ccccc1=2

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NCEH1 Q6PIU2 1/20 0.35
GCGR P47871 1/20 0.35
MAPT P10636 1/20 0.34
KDM4E B2RXH2 3/20 0.33
ALDH1A1 P00352 2/20 0.33
HPGD P15428 2/20 0.33
HSD17B10 Q99714 2/20 0.33
DCTPP1 Q9H773 1/20 0.33
TLR8 Q9NR97 1/20 0.33
CYP1A1 P04798 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
CTRC Q99895 1/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ELANE P08246 1/20 0.31
CTSG P08311 1/20 0.31
CYP1A2 P05177 1/20 0.31
CYP3A4 P08684 1/20 0.31
TSHR P16473 1/20 0.31
LMNA P02545 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1884685 0.85 KDM4E (0.36) NCEH1KDM4EALDH1A1HPGDRAB9A
SCHEMBL1888553 0.83 TLR8 (0.35) KDM4EALDH1A1HPGDTLR8CTRC
SCHEMBL1883021 0.83 TLR8 (0.35) KDM4EALDH1A1HPGDTLR8CTRC
SCHEMBL27771377 0.82 ELANE (0.36) GCGRMAPTKDM4EALDH1A1HPGD
SCHEMBL1883533 0.81 ELANE (0.35) GCGRMAPTKDM4EALDH1A1HPGD
SCHEMBL1885411 0.75 TLR8 (0.36) MAPTALDH1A1HPGDTLR8NPC1
SCHEMBL27727012 0.75 GCGR (0.48) GCGRHPGDDCTPP1SMN1; SMN2
SCHEMBL1879185 0.74 ELANE (0.35) GCGRTLR8ELANECTSGCYP3A4
SCHEMBL674883 0.73 ELANE (0.36) KDM4EALDH1A1HPGDHSD17B10TLR8
SCHEMBL27771300 0.73 ELANE (0.36) MAPTKDM4EALDH1A1HPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-20100104879-A1 CLEAR HARD COAT FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND DISPLAY DEVICE EMPLOYING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed