SCHEMBL1879185

SCHEMBL1879185

CCCCc1ccc(-c2c(-c3ccc(CCCC)c(CC)c3CCCC)c(-c3ccc(CCCC)c(CC)c3CCCC)c3c(c2-c2ccc(CCCC)c(CC)c2CCCC)=c2ccccc2=3)c(CCCC)c1CC

nearest known ligand 0.35

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
ELANE P08246 4/20 0.35
CTSG P08311 4/20 0.35
TYR P14679 1/20 0.32
LIPG Q9Y5X9 1/20 0.31
TLR8 Q9NR97 1/20 0.31
GCGR P47871 1/20 0.30
CYP3A4 P08684 1/20 0.30
CYP2D6 P10635 1/20 0.30
CYP2C9 P11712 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL674883 0.94 ELANE (0.36) ELANECTSGTYRLIPGTLR8
SCHEMBL1883533 0.90 ELANE (0.35) ELANECTSGGCGR
SCHEMBL1888946 0.83 KDM4E (0.31) CYP2D6
SCHEMBL27771311 0.83 ELANE (0.36) ELANECTSGTYR
SCHEMBL27719090 0.77 ELANE (0.37) ELANECTSGTYRLIPGTLR8
SCHEMBL27747978 0.76 HSD11B1 (0.41) ELANECTSGGCGRCYP2C9
SCHEMBL5180423 0.75 GPR3 (0.44) TLR8
SCHEMBL1887868 0.75 TLR8 (0.34) ELANECTSGTYRLIPGTLR8
SCHEMBL27747981 0.75 GCGR (0.39) ELANECTSGGCGR
SCHEMBL1890837 0.74 NCEH1 (0.35) ELANECTSGTLR8GCGRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7947342-B2 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2011-05-24 US disclosed
US-20100104879-A1 CLEAR HARD COAT FILM, ANTI-REFLECTION FILM, POLARIZING PLATE AND DISPLAY DEVICE EMPLOYING THE SAME KONICA MINOLTA OPTO, INC. (JP) 2010-04-29 US disclosed
EP-2012150-A1 POLARIZING PLATE PROTECTION FILM, METHOD FOR PRODUCING THE SAME, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY Konica Minolta Opto, Inc. (JP) 2009-01-07 EP disclosed
US-20070254115-A1 Polarizer protective film, manufacturing method thereof, polarizing plate and liquid crystal display KONICA MINOLTA OPTO, INC. (JP) 2007-11-01 US disclosed