⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5801975 | 0.75 | — | — | |
| SCHEMBL14028740 | 0.74 | ALDH1A1 (0.42) | — | |
| SCHEMBL1004712 | 0.70 | — | — | |
| SCHEMBL18930136 | 0.54 | — | — | |
| SCHEMBL21320415 | 0.54 | — | — | |
| SCHEMBL8839051 | 0.52 | — | — | |
| SCHEMBL14791701 | 0.52 | — | — | |
| SCHEMBL8839052 | 0.52 | — | — | |
| SCHEMBL10103187 | 0.51 | — | — | |
| SCHEMBL806040 | 0.51 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10188660-B2 | Anti-huLRRC15 antibody drug conjugates and methods for their use | ABBVIE INC. (US) | 2019-01-29 | — | — | US | disclosed |
| US-20170151343-A1 | ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE | ABBVIE INC. | 2017-06-01 | — | — | US | disclosed |