SCHEMBL18909175

SCHEMBL18909175

Nc1nc2sc3ncsc3c2s1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
MAPK1 P28482 1/20 0.42
HSD17B10 Q99714 1/20 0.42
SMN1; SMN2 Q16637 2/20 0.33
PI4KA P42356 1/20 0.31
PI4K2B Q8TCG2 1/20 0.31
PI4K2A Q9BTU6 1/20 0.31
PI4KB Q9UBF8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15437033 0.80 HSD17B10 (0.58) GAAMAPTMAPK1HSD17B10SMN1; SMN2
SCHEMBL16438236 0.76 KDM4E (0.33) MAPK1HSD17B10
SCHEMBL22045712 0.76
SCHEMBL18909172 0.74
SCHEMBL18309106 0.72 TLR8 (0.33)
SCHEMBL18909182 0.67 ALDH1A1 (0.44) GAAMAPTHSD17B10SMN1; SMN2PI4KA
SCHEMBL5041922 0.62 MGAM (0.31) GAAHSD17B10
SCHEMBL6003639 0.61 HSD17B10 (0.46) GAAMAPTMAPK1HSD17B10SMN1; SMN2
SCHEMBL5040395 0.60 HSD17B10 (0.69) GAAMAPTMAPK1HSD17B10SMN1; SMN2
SCHEMBL18909173 0.60

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017089952-A1 DEGRADABLE CONJUGATED POLYMERS The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel (US) 2017-06-01 WO disclosed