SCHEMBL18909183

SCHEMBL18909183

Nc1cc2oc3ccsc3c2s1

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
PIK3R2 O00459 1/20 0.33
PIK3CA P42336 1/20 0.33
PIK3CB P42338 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10005483 0.78 PIK3R2 (0.39) PIK3R2PIK3CAPIK3CB
SCHEMBL17432125 0.77 PIK3R2 (0.33) PIK3R2PIK3CAPIK3CB
SCHEMBL18909187 0.64 GPR35 (0.35)
SCHEMBL4428271 0.64 CYP2A6 (0.33)
SCHEMBL19101288 0.63 PIK3R2 (0.33) PIK3R2PIK3CAPIK3CB
SCHEMBL18909170 0.63 GPR35 (0.34)
SCHEMBL18909198 0.61 GPR35 (0.33)
SCHEMBL17934679 0.60 CYP2A6 (0.31)
SCHEMBL11924881 0.60 PIK3R2 (0.38) PIK3R2PIK3CAPIK3CB
SCHEMBL18909202 0.59 GPR35 (0.32)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017089952-A1 DEGRADABLE CONJUGATED POLYMERS The Board of Trustees of the Leland Stanford Junior University Office of the General Counsel (US) 2017-06-01 WO disclosed