SCHEMBL18909522

SCHEMBL18909522

Cc1ccc(-c2ccc(N(c3ccccc3)c3ccc(-c4ncccn4)cc3)cc2)cc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CLK4 Q9HAZ1 1/20 0.42
ALDH1A1 P00352 5/20 0.40
RAB9A P51151 4/20 0.40
NPC1 O15118 4/20 0.40
NFKB1 P19838 3/20 0.40
NFKB2 Q00653 3/20 0.40
RELA Q04206 3/20 0.40
MEN1 O00255 2/20 0.39
KMT2A Q03164 2/20 0.39
NR1H2 P55055 1/20 0.39
NR1H3 Q13133 1/20 0.39
TP53 P04637 2/20 0.39
PKM P14618 1/20 0.39
SMN1; SMN2 Q16637 4/20 0.38
CYP1A2 P05177 3/20 0.38
CYP2C19 P33261 3/20 0.38
KDM4E B2RXH2 3/20 0.38
TDP1 Q9NUW8 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP2D6 P10635 2/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21019138 0.97 NPC1 (0.44) CLK4ALDH1A1RAB9ANPC1NFKB1
SCHEMBL21018825 0.93 CLK4 (0.47) CLK4ALDH1A1RAB9ANPC1NFKB1
SCHEMBL16614434 0.88 SMN1; SMN2 (0.47) CLK4ALDH1A1RAB9ANPC1NFKB1
SCHEMBL6449344 0.85 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1NFKB1NFKB2
SCHEMBL12593268 0.85 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1NFKB1NFKB2
SCHEMBL12781330 0.85 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1NFKB1NFKB2
SCHEMBL21919140 0.85 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1NFKB1NFKB2
SCHEMBL10075958 0.85 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1NFKB1NFKB2
SCHEMBL12619867 0.85 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1NFKB1NFKB2
SCHEMBL13930211 0.85 ALDH1A1 (0.50) ALDH1A1RAB9ANPC1NFKB1NFKB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2017090918-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT USING SAME, AND ELECTRONIC DEVICE COMPRISING SAME 덕산네오룩스 주식회사 2017-06-01 WO disclosed