Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 3/20 | 0.69 |
| ▸ | ACE | P12821 | 2/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | MMP2 | P08253 | 1/20 | 0.61 |
| ▸ | MMP9 | P14780 | 1/20 | 0.61 |
| ▸ | MMP8 | P22894 | 1/20 | 0.61 |
| ▸ | MMP14 | P50281 | 1/20 | 0.61 |
| ▸ | ANPEP | P15144 | 2/20 | 0.60 |
| ▸ | IL1RN | P18510 | 2/20 | 0.60 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23380923 | 0.89 | ECE1 (0.69) | ECE1ACEKDM4EMAPTMMP2 | |
| SCHEMBL19929604 | 0.88 | ECE1 (0.77) | ECE1ACEMMP9MMP8 | |
| SCHEMBL2183808 | 0.88 | ECE1 (0.64) | ECE1ACEMMP2MMP9MMP8 | |
| SCHEMBL2183816 | 0.88 | ECE1 (0.64) | ECE1ACEMMP2MMP9MMP8 | |
| SCHEMBL30799684 | 0.88 | ECE1 (0.64) | ECE1 | |
| SCHEMBL22133113 | 0.88 | ECE1 (0.64) | ECE1 | |
| SCHEMBL13725698 | 0.88 | ECE1 (0.64) | ECE1 | |
| SCHEMBL13784699 | 0.87 | ECE1 (0.69) | ECE1ACEKDM4EMAPTMMP2 | |
| SCHEMBL8905663 | 0.86 | ECE1 (0.74) | ECE1ACEMMP9MMP8ANPEP | |
| SCHEMBL16566050 | 0.86 | ECE1 (0.74) | ECE1ACEMMP9MMP8ANPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170151339-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | TVA (ABC), LLC | 2017-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170151339-A1 | TARGETED CONJUGATES AND PARTICLES AND FORMULATIONS THEREOF | CD47, CD44, FURIN | ECE1 1262/4885ACE 1490/4885KDM4E 4628/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.