Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ECE1 | P42892 | 9/20 | 0.74 |
| ▸ | ACE | P12821 | 2/20 | 0.64 |
| ▸ | GHSR | Q92847 | 3/20 | 0.64 |
| ▸ | ANPEP | P15144 | 2/20 | 0.58 |
| ▸ | IL1RN | P18510 | 2/20 | 0.58 |
| ▸ | ERAP2 | Q6P179 | 2/20 | 0.58 |
| ▸ | ERAP1 | Q9NZ08 | 2/20 | 0.58 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.58 |
| ▸ | CTSC | P53634 | 1/20 | 0.57 |
| ▸ | MMP1 | P03956 | 1/20 | 0.57 |
| ▸ | MMP3 | P08254 | 1/20 | 0.57 |
| ▸ | MMP9 | P14780 | 1/20 | 0.57 |
| ▸ | MMP8 | P22894 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16566050 | 1.00 | ECE1 (0.74) | ECE1ACEGHSRANPEPIL1RN | |
| SCHEMBL23875110 | 0.93 | ECE1 (0.64) | ECE1ACEGHSRCTSCMMP1 | |
| SCHEMBL19929604 | 0.93 | ECE1 (0.77) | ECE1ACEMMP1MMP3MMP9 | |
| SCHEMBL29400177 | 0.90 | ACE (0.78) | ECE1ACE | |
| SCHEMBL9235805 | 0.90 | ACE (0.78) | ECE1ACE | |
| SCHEMBL2488765 | 0.90 | ACE (0.78) | ECE1ACE | |
| SCHEMBL1228369 | 0.90 | ACE (0.78) | ECE1ACE | |
| SCHEMBL9235801 | 0.90 | ACE (0.78) | ECE1ACE | |
| SCHEMBL30799670 | 0.89 | GHSR (0.68) | ECE1ACEGHSRERAP2MMP1 | |
| SCHEMBL5558360 | 0.89 | ECE1 (0.69) | ECE1ACEGHSRCTSC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021102052-A1 | DIRECTED CONJUGATION TECHNOLOGIES | KLEO PHARMACEUTICALS, INC. (US) | 2021-05-27 | — | — | WO | disclosed |
| EP-0753004-A1 | ANTAGONISTS OF ENDOTHELIN RECEPTORS | Japat Ltd (CH) | 1997-01-15 | — | — | EP | disclosed |