SCHEMBL18910973

SCHEMBL18910973

CC(C)(CS)C(=O)[C@H](CCCNC(N)=O)NC(=O)[C@H](CO)NC(=O)CCCCCN1C(=O)C=CC1=O

nearest known ligand 0.43

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
▸ NMT1 P30419 11/20 0.40
▸ NMT2 O60551 10/20 0.40
▸ TLR2 O60603 1/20 0.38
▸ PTGS1 P23219 4/20 0.35
▸ PTGS2 P35354 4/20 0.35
▸ NPY4R P50391 2/20 0.35
▸ NPY1R P25929 1/20 0.35
▸ NPY2R P49146 1/20 0.35
▸ NPY5R Q15761 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20889009 0.91 NMT1 (0.41) NMT1NMT2TLR2PTGS1PTGS2
SCHEMBL20340675 0.91 NMT1 (0.43) NMT1NMT2TLR2PTGS1PTGS2
SCHEMBL17722904 0.87 NMT1 (0.45) NMT1NMT2TLR2PTGS1PTGS2
SCHEMBL22668934 0.85 NPY4R (0.38) NMT1NMT2TLR2PTGS1PTGS2
SCHEMBL19681343 0.85 NMT1 (0.46) NMT1NMT2TLR2PTGS1PTGS2
SCHEMBL24780979 0.84 NMT1 (0.44) NMT1NMT2TLR2NPY4RNPY1R
SCHEMBL22668929 0.83 PTGS1 (0.44) NMT1NMT2PTGS1PTGS2NPY4R
SCHEMBL20889000 0.83 NMT1 (0.46) NMT1NMT2TLR2NPY4RNPY1R
SCHEMBL23436462 0.83 NMT1 (0.46) NMT1NMT2TLR2NPY4RNPY1R
SCHEMBL19681474 0.81 NPY5R (0.39) NMT1NMT2PTGS1PTGS2NPY4R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20220396631-A1 TRISPECIFIC BINDING MOLECULES AGAINST BCMA AND USES THEREOF NOVARTIS AG (CH) 2022-12-15 — — US disclosed
US-10195209-B2 Anti-huLRRC15 antibody drug conjugates and methods for their use ABBVIE INC. (US) 2019-02-05 — — US disclosed
US-20170151344-A1 ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE ABBVIE INC. 2017-06-01 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170151344-A1 ANTI-huLRRC15 ANTIBODY DRUG CONJUGATES AND METHODS FOR THEIR USE LRRC59, LRRC47, HACD3 NMT1 1208/4885NMT2 1110/4885TLR2 2881/4885
US-20220396631-A1 TRISPECIFIC BINDING MOLECULES AGAINST BCMA AND USES THEREOF CD2, CD2BP2, CD22 NMT1 1317/4885NMT2 1971/4885TLR2 1223/4885
US-10195209-B2 Anti-huLRRC15 antibody drug conjugates and methods for their use LRRC59, LRRC47, HACD3 NMT1 1208/4885NMT2 1110/4885TLR2 2881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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