SCHEMBL18911985

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL18912167	0.87	GRIN2B (0.52)	HTR2AHTR2CGRIN2BNPY5RKMT2A
	SCHEMBL21872944	0.85	HTR2C (0.46)	HTR2AHTR2CGRIN2BCYP1A2CYP3A4
	SCHEMBL21936469	0.83	GRIN2B (0.55)	HTR2AHTR2CGRIN2BGRIN1KCNH2
	SCHEMBL10165538	0.83	GRIN2B (0.55)	HTR2AHTR2CGRIN2BNPY5RGRIN1
	SCHEMBL18911988	0.83	NPY5R (0.43)	HTR2AHTR2CGRIN2BCYP3A4CYP2C9
	SCHEMBL21872463	0.81	HTR2C (0.43)	HTR2AHTR2CGRIN2BCYP1A2CYP3A4
	SCHEMBL18911998	0.79	HTR2A (0.40)	HTR2AHTR2CCYP1A2CYP3A4CYP2C9
	SCHEMBL18911877	0.77	HTR2C (0.53)	HTR2AHTR2CGRIN2BCYP1A2CYP3A4
	SCHEMBL31177216	0.77	HTR2C (0.55)	HTR2AHTR2CGRIN2BNPY5RLMNA
	SCHEMBL2014724	0.77	HTR2C (0.55)	HTR2AHTR2CNPY5RLMNAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.