Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18894874 | 0.93 | TSHR (0.51) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL26078289 | 0.89 | SMN1; SMN2 (0.58) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL18895074 | 0.87 | TSHR (0.46) | SMN1; SMN2MEN1KMT2ATSHRALDH1A1 | |
| SCHEMBL28619851 | 0.86 | TSHR (0.45) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL278334 | 0.84 | TSHR (0.63) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL51038 | 0.81 | ALDH1A1 (0.55) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL29219910 | 0.77 | ALDH1A1 (0.47) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL25003537 | 0.77 | ALDH1A1 (0.38) | SMN1; SMN2LMNAMEN1KMT2ATSHR | |
| SCHEMBL11987592 | 0.77 | ALDH1A1 (0.50) | SMN1; SMN2LMNATSHRALDH1A1HPGD | |
| SCHEMBL11805964 | 0.77 | ALDH1A1 (0.45) | SMN1; SMN2LMNAMEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018093413-A1 | ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) | ARCHER DANIELS MIDLAND COMPANY (US) | 2018-05-24 | — | — | WO | disclosed |
| WO-2017091437-A1 | ORGANOTIN CATALYSTS IN ESTERIFICATION PROCESSES OF FURAN-2,5-DICARBOXYLIC ACID (FDCA) | ARCHER DANIELS MIDLAND COMPANY (US) | 2017-06-01 | — | — | WO | disclosed |