Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | GGPS1 | O95749 | 6/20 | 0.39 |
| ▸ | FDPS | P14324 | 9/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.38 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.37 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2397669 | 1.00 | TSHR (0.44) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL517658 | 1.00 | TSHR (0.44) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL518405 | 1.00 | TSHR (0.44) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL517884 | 1.00 | TSHR (0.44) | TSHRTHRBGGPS1FDPSEPHX1 | |
| Bromide SCHEMBL31470931 | 0.97 | TSHR (0.42) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL518098 | 0.97 | TSHR (0.39) | TSHRTHRBGGPS1FDPSSMPD1 | |
| SCHEMBL479334 | 0.90 | EPHX1 (0.38) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL18457877 | 0.90 | TSHR (0.40) | TSHRTHRBGGPS1FDPSEPHX1 | |
| SCHEMBL517449 | 0.88 | TSHR (0.35) | TSHRTHRBFDPSEPHX1 | |
| SCHEMBL3431417 | 0.86 | TSHR (0.35) | TSHRTHRBGGPS1FDPSEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7939562-B2 | fatty acid chain are derived from natural vegetable oils such as vernonia oil, lesquerella oil and castor oil, in which the several reactive groups such as epoxy, hydroxy and double bonds can be modified to polar and ionic groups | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DEVELOPMENT AUTHORITY (IL) | 2011-05-10 | — | — | US | disclosed |
| EP-1360168-A4 | AMPHIPHILIC DERIVATIVES FOR THE PRODUCTION OF VESICLES, MICELLES AND COMPLEXANTS, AND PRECURSORS THEREOF | UNIV BEN GURION (IL) | 2007-10-31 | — | — | EP | disclosed |
| US-20050118248-A1 | Amphiphilic derivatives for the production of vesicles, micelles and complexants, and precursors thereof | BEN-GURION UNIVERSITY OF THE NEGEV RESEARCH AND DE (IL) | 2005-06-02 | — | — | US | disclosed |
| EP-1360168-A2 | AMPHIPHILIC DERIVATIVES FOR THE PRODUCTION OF VESICLES, MICELLES AND COMPLEXANTS, AND PRECURSORS THEREOF | Ben Gurion University Of The Negev Research And Development Authority (IL) | 2003-11-12 | — | — | EP | disclosed |
| WO-2002055011-A2 | AMPHIPHILIC DERIVATIVES FOR THE PRODUCTION OF VESICLES, MICELLES AND COMPLEXANTS, AND PRECURSORS THEREOF | UNIV BEN GURION (IL) | 2002-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050118248-A1 | Amphiphilic derivatives for the production of vesicles, micelles and complexants, and precursors thereof | CHMP4B, LIPA, VPS4B | TSHR 4405/4885THRB 3877/4885GGPS1 359/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.