SCHEMBL1891371

SCHEMBL1891371

CCOC(=O)CC(=O)C(C)F

nearest known ligand 0.58

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.58
MGAM O43451 1/20 0.58
SI P14410 1/20 0.58
MGAM2 Q2M2H8 1/20 0.58
ALDH1A1 P00352 4/20 0.43
TRPA1 O75762 1/20 0.43
LMNA P02545 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.38
CYP1A2 P05177 1/20 0.38
HSD17B10 Q99714 1/20 0.37
KMT2A Q03164 3/20 0.36
POLB P06746 1/20 0.36
ALOX15 P16050 2/20 0.36
SOAT1 P35610 1/20 0.36
KDM4E B2RXH2 1/20 0.35
MEN1 O00255 1/20 0.35
TSHR P16473 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18890 0.84 GAA (0.61) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7100929 0.83 MGAM (0.38) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL29010309 0.83 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
Silver SCHEMBL30466756 0.83 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL17275135 0.83 GAA (0.58) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL182126 0.82 GAA (0.64) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7097261 0.81 TSHR (0.41) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL7096992 0.81 GAA (0.56) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL17275136 0.81 GAA (0.56) GAAMGAMSIMGAM2ALDH1A1
SCHEMBL16481526 0.81 GAA (0.56) GAAMGAMSIMGAM2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118307408-B Preparation method of ethyl 2-fluoropropionylacetate 上海恩氟佳科技有限公司 2025-03-21 CN claimed
CN-118307408-A Preparation method of ethyl 2-fluoropropionylacetate 上海恩氟佳科技有限公司 2024-07-09 CN claimed
CN-111293363-B High-voltage lithium nickel manganese oxide lithium ion battery electrolyte and secondary battery containing same 广西民族师范学院 2022-08-26 CN claimed
CN-103896855-B The synthetic method of the fluoro-6-chlorine of a kind of 4-(1-bromoethyl)-5-pyrimidine TECHNOLOGY CENTER OF JUHUA GROUP (CN) 2016-05-18 CN claimed
CN-103896855-A Method for synthesizing 4-(1-bromoethyl) -5-fluoro-6-chloropyrimidine JUHUA GROUP TECHNOLOGY CT 2014-07-02 CN claimed
CN-118307408-B Preparation method of ethyl 2-fluoropropionylacetate 上海恩氟佳科技有限公司 2025-03-21 CN disclosed
CN-118307408-B Preparation method of ethyl 2-fluoropropionylacetate 上海恩氟佳科技有限公司 2025-03-21 CN disclosed
CN-118307408-A Preparation method of ethyl 2-fluoropropionylacetate 上海恩氟佳科技有限公司 2024-07-09 CN disclosed
CN-118307408-A Preparation method of ethyl 2-fluoropropionylacetate 上海恩氟佳科技有限公司 2024-07-09 CN disclosed
CN-118307408-A Preparation method of ethyl 2-fluoropropionylacetate 上海恩氟佳科技有限公司 2024-07-09 CN disclosed
CN-115724829-A Liquid chromatography preparation method for separating impurities of fungal drug intermediate 天津力生制药股份有限公司 2023-03-03 CN disclosed
CN-111293363-B High-voltage lithium nickel manganese oxide lithium ion battery electrolyte and secondary battery containing same 广西民族师范学院 2022-08-26 CN disclosed
EP-1038861-B1 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME UBE INDUSTRIES (JP) 2003-09-03 EP disclosed
US-6593488-B1 Reacting 2-fluorocarboxylate with carboxylate UBE INDUSTRIES, LTD. (JP) 2003-07-15 US disclosed
US-6340757-B1 SYNTHETIC INTERMEDIATE FOR AMINOPYRIMIDINE DERIVATIVES WHICH ARE USEFUL AS ACARICIDES, FUNGICIDES OR NEMATOCIDES, AND PROCESSES FOR PRODUCING THE SAME. UBE INDUSTRIES, LTD. (JP) 2002-01-22 US disclosed
EP-1065202-A1 6-(ALPHA-FLUOROALKYL)-4-PYRIMIDONES AND PROCESS FOR PRODUCING THE SAME UBE INDUSTRIES LIMITED (JP) 2001-01-03 EP disclosed
EP-1038861-A1 4-FLUORO-3-OXOCARBOXYLIC ESTERS AND PROCESS FOR PRODUCING THE SAME UBE INDUSTRIES LIMITED (JP) 2000-09-27 EP disclosed
US-5567817-A Triazole antifungal agents PFIZER INC. (US) 1996-10-22 US disclosed
EP-0440372-B1 TRIAZOLE ANTIFUNGAL AGENTS Pfizer Limited (GB) 1993-06-02 EP disclosed
EP-0440372-A1 Triazole antifungal agents Pfizer Limited (GB) 1991-08-07 EP disclosed