Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | MGAM | O43451 | 1/20 | 0.61 |
| ▸ | SI | P14410 | 1/20 | 0.61 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29010309 | 0.98 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| Silver SCHEMBL30466756 | 0.98 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL17275135 | 0.98 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL17275136 | 0.96 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL25711754 | 0.90 | GAA (0.54) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL17275156 | 0.86 | GAA (0.45) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL1891371 | 0.84 | GAA (0.58) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL28924679 | 0.83 | CES2 (0.41) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL7096992 | 0.83 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 | |
| SCHEMBL16481526 | 0.83 | GAA (0.56) | GAAMGAMSIMGAM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1087 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119930595-A | Synthetic process of isoxazoline derivative | 江苏剑牌农化股份有限公司 | 2025-05-06 | — | — | CN | claimed |
| CN-119882351-A | High-adhesion positive KrF photoresist resin composition | 万华化学集团股份有限公司 | 2025-04-25 | — | — | CN | claimed |
| CN-119101010-B | Difluoromethyl thiazole amide-containing compound and application thereof as bactericide | 安徽理工大学 | 2025-04-04 | — | — | CN | claimed |
| CN-119591545-A | Synthesis method of difluoro pyrazole acid and ester and intermediate thereof | 湖北晟康化工有限公司 | 2025-03-11 | — | — | CN | claimed |
| CN-118702572-A | Synthesis method of ethyl 2-ethoxymethylene-4, 4-difluoro-3-oxobutyrate | 苏利(宁夏)新材料科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-114315577-B | Synthesis method of 2-ethoxymethylene-4, 4-difluoro acetoacetic acid ethyl ester | 湖南海利化工股份有限公司 | 2024-09-13 | — | — | CN | claimed |
| CN-118420467-B | Method for separating methyl acetate/ethyl acetate-methanol/ethanol-water mixed solution by using NMP waste liquid | 湖南工程学院 | 2024-08-30 | — | — | CN | claimed |
| CN-118420467-A | Method for separating methyl acetate/ethyl acetate-methanol/ethanol-water mixed solution by using NMP waste liquid | 湖南工程学院 | 2024-08-02 | — | — | CN | claimed |
| CN-118063317-B | Preparation method of 4, 4-difluoro acetoacetic acid ethyl ester | 江西农业大学 | 2024-06-21 | — | — | CN | claimed |
| CN-118063317-A | Preparation method of 4, 4-difluoro acetoacetic acid ethyl ester | 江西农业大学 | 2024-05-24 | — | — | CN | claimed |
| CN-107876092-A | The high stability titanium catalyst of ester exchange carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2018-04-06 | — | — | CN | claimed |
| CN-107501182-A | The trifluoromethyl of 1 substituted-phenyl 5（Difluoromethyl）4 pyrazole carboxylic acid synthetic methods | 中国农业大学 | 2017-12-22 | — | — | CN | claimed |
| CN-107417719-A | A kind of titanium chelate catalyst for being used for carbonate synthesis benzene methyl and diphenyl carbonate | 华东理工大学 | 2017-12-01 | — | — | CN | claimed |
| EP-2571854-B1 | METHOD FOR MANUFACTURING 1-ALKYL-3-DIFLUORMETHYL-5-HYDROXYPYRAZOLES | BAYER IP GMBH (DE) | 2014-11-05 | — | — | EP | claimed |
| US-8455664-B2 | Process for preparing 1-alkyl-3-difluoromethyl-5-hydroxypyrazoles | BAYER CROPSCIENCE AG (DE) | 2013-06-04 | — | — | US | claimed |
| EP-2571854-A1 | METHOD FOR MANUFACTURING 1 - ALKYL - 3 - DIFLUORMETHYL - 5 - HYDROXYPYRAZOLES | Bayer Intellectual Property GmbH (DE) | 2013-03-27 | — | — | EP | claimed |
| US-20110288304-A1 | Process for Preparing 1-Alkyl-3-difluoromethyl-5-hydroxypyrazoles | BAYER CROPSCIENCE AG (DE) | 2011-11-24 | — | — | US | claimed |
| WO-2011144549-A1 | METHOD FOR MANUFACTURING 1 - ALKYL - 3 - DIFLUORMETHYL - 5 - HYDROXYPYRAZOLES | BAYER CROPSCIENCE AG (DE) | 2011-11-24 | — | — | WO | claimed |
| EP-0135491-B1 | HERBICIDAL 2,6-BIS-FLUOROMETHYL-DIHYDROPYRIDINE-3,5-DICARBOXYLIC ACID ESTERS | MONSANTO COMPANY (US) | 1989-01-25 | — | — | EP | claimed |
| EP-0135491-A1 | Herbicidal 2,6-bis-fluoromethyl-dihydropyridine-3,5-dicarboxylic acid esters | MONSANTO COMPANY (US) | 1985-03-27 | — | — | EP | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288304-A1 | Process for Preparing 1-Alkyl-3-difluoromethyl-5-hydroxypyrazoles | CYP51A1, CYP3A5, CYP4F3 | GAA 507/4885MGAM 278/4885SI 667/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.