Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14945135 | 0.88 | ACACB (0.38) | ACACBALDH1A1MAPTRXFP1 | |
| SCHEMBL19361562 | 0.84 | ALDH1A1 (0.38) | ACACBALDH1A1MAPTRXFP1 | |
| SCHEMBL19369287 | 0.82 | ALDH1A1 (0.31) | ALDH1A1 | |
| SCHEMBL14945336 | 0.80 | ACACB (0.34) | ACACBALDH1A1MAPTRXFP1 | |
| SCHEMBL14945334 | 0.80 | ALDH1A1 (0.30) | ALDH1A1MAPTRXFP1 | |
| SCHEMBL16920270 | 0.79 | ALDH1A1 (0.30) | ALDH1A1MAPTRXFP1 | |
| SCHEMBL19348115 | 0.78 | ALDH1A1 (0.36) | ACACBALDH1A1MAPT | |
| SCHEMBL14945492 | 0.77 | ALDH1A1 (0.31) | ACACBALDH1A1MAPTRXFP1 | |
| SCHEMBL18914284 | 0.77 | ACACB (0.35) | ACACB | |
| SCHEMBL20867527 | 0.76 | ALDH1A1 (0.33) | ACACBALDH1A1MAPTRXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017091600-A1 | PYRAZOLE ACC INHIBITORS AND USES THEREOF | GILEAD APOLLO, LLC (US) | 2017-06-01 | — | — | WO | disclosed |