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SCHEMBL18914616

SCHEMBL18914616

C#CCN(c1ccccc1)c1cccc(Oc2cccc(Oc3cc4c(cc3Oc3cccc(Oc5cccc(N(CC#C)c6ccccc6)c5)c3C#N)C3(CC4(C)C)CC(C)(C)c4cc(Oc5cccc(Oc6cccc(N(CC#C)c7ccccc7)c6)c5C#N)c(Oc5cccc(Oc6cccc(N(CC#C)c7ccccc7)c6)c5C#N)cc43)c2C#N)c1

nearest known ligand 0.33

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ HSD11B1 P28845 1/20 0.33
▸ MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18907153 0.93 — —
SCHEMBL18914617 0.91 MEN1 (0.32) HSD11B1
SCHEMBL18914473 0.85 MEN1 (0.32) HSD11B1
SCHEMBL18907152 0.84 — —
SCHEMBL20091518 0.84 HSD11B1 (0.31) HSD11B1
SCHEMBL18914615 0.81 AR (0.30) HSD11B1
SCHEMBL17430346 0.80 GAA (0.37) HSD11B1MAPT
SCHEMBL18914614 0.80 MAPT (0.35) MAPT
SCHEMBL18914472 0.79 BRAF (0.31) —
SCHEMBL17430390 0.79 MAPT (0.39) MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180114698-A2 COMPOSITION FOR FILM FORMATION, FILM, PRODUCTION METHOD OF PATTERNED SUBSTRATE, AND COMPOUND JSR CORPORATION (JP) 2018-04-26 — — US disclosed
US-20170154782-A1 COMPOSITION FOR FILM FORMATION, FILM, PRODUCTION METHOD OF PATTERNED SUBSTRATE, AND COMPOUND JSR CORPORATION (JP) 2017-06-01 — — US disclosed