SCHEMBL189164

SCHEMBL189164

C1=CCC2CCCCC2C1

nearest known ligand 0.50

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6155112 0.96 ALDH1A1 (0.47) ALDH1A1
SCHEMBL122871 0.96 ALDH1A1 (0.47) ALDH1A1
SCHEMBL188708 0.92
SCHEMBL11867125 0.92
SCHEMBL6738460 0.89 ALDH1A1 (0.38) ALDH1A1
SCHEMBL14218207 0.89 ALDH1A1 (0.57) ALDH1A1
SCHEMBL23421864 0.87 ALDH1A1 (0.39) ALDH1A1
SCHEMBL10846656 0.87 ALDH1A1 (0.39) ALDH1A1
SCHEMBL10846654 0.87 ALDH1A1 (0.39) ALDH1A1
SCHEMBL2001108 0.85 ALDH1A1 (0.44) ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8389752-B2 Preparation of alicyclic diepoxides Peomerus LLC (US) 2013-03-05 US claimed
US-12577219-B2 Macrolide brefeldin a ester derivatives and use thereof OCEAN UNIVERSITY OF CHINA (CN) 2026-03-17 US disclosed
US-20250149586-A1 ETHYLENIC POLYMER PARTICLE, METHOD FOR PRODUCING ETHYLENIC POLYMER PARTICLE, STRETCH-MOLDED BODY, METHOD FOR PRODUCING STRETCH-MOLDED BODY, AND USE OF SAME MITSUI CHEMICALS, INC. (JP) 2025-05-08 US disclosed
US-20250100966-A1 MEK INHIBITORS AND METHODS OF THEIR USE EXELIXIS INC (US) 2025-03-27 US disclosed
EP-3805234-B1 AROMATIC HETEROCYCLIC COMPOUND, AND PHARMACEUTICAL COMPOSITION AND USE THEREOF GUANGZHOU HENOVCOM BIOSCIENCE CO LTD (CN) 2024-09-04 EP disclosed
CN-114989173-B Imidazole compound, pharmaceutical composition and application thereof 广州市恒诺康医药科技有限公司 2024-03-19 CN disclosed
CN-117510500-A Preparation method of asperazepanones alkaloid and application of asperazepanones alkaloid as anti-inflammatory drug 中国海洋大学 2024-02-06 CN disclosed
WO-2023190212-A1 METHOD FOR PRODUCING OLEFIN POLYMER 三井化学株式会社 2023-10-05 WO disclosed
US-11762248-B2 Light control film and liquid crystal display device NITTO DENKO CORPORATION (JP) 2023-09-19 US disclosed
CN-116726010-A Application of macrolide derivative in preparation of medicines for inhibiting pro-inflammatory cytokine acting agents 中国海洋大学 2023-09-12 CN disclosed
WO-2004006846-A2 RECEPTOR-TYPE KINASE MODULATORS AND METHODS OF USE EXELIXIS, INC. (US) 2004-01-22 WO disclosed
WO-2003093297-A2 PROTEIN KINASE MODULATORS AND METHODS OF USE EXELIXIS, INC. (US) 2003-11-13 WO disclosed
EP-0934302-A2 AMINOPHENOL DERIVATES BAYER AG (DE) 1999-08-11 EP disclosed
WO-1998016522-A2 AMINOPHENOL DERIVATES WITH FUNGICIDAL PROPERTY BAYER AKTIENGESELLSCHAFT (DE) 1998-04-23 WO disclosed
US-5032470-A Corrosion resistance MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1991-07-16 US disclosed
EP-0410605-A2 Process for producing a polymer by ring-opening polymerization NIPPON ZEON CO., LTD. (JP) 1991-01-30 EP disclosed
EP-0405843-A2 Molding material NIPPON ZEON CO., LTD. (JP) 1991-01-02 EP disclosed
EP-0367589-A2 Optical recording media MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-05-09 EP disclosed
EP-0358516-A2 Process for producing cycloolefin random copolymers MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1990-03-14 EP disclosed
EP-0301830-A2 Resin composition for spacers of information recording disc MITSUI PETROCHEMICAL INDUSTRIES, LTD. (JP) 1989-02-01 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12577219-B2 Macrolide brefeldin a ester derivatives and use thereof BCL6, BCL6B, BCL3 ALDH1A1 4400/4885
US-20250100966-A1 MEK INHIBITORS AND METHODS OF THEIR USE BRAF, NRAS, KRAS ALDH1A1 1194/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.