Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 18/20 | 0.42 |
| ▸ | PDCD1 | Q15116 | 2/20 | 0.41 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2128410 | 0.90 | AVPR2 (0.43) | AVPR2PDCD1CD274 | |
| SCHEMBL2705389 | 0.89 | AVPR2 (0.42) | AVPR2PDCD1CD274 | |
| SCHEMBL2704506 | 0.87 | AVPR2 (0.44) | AVPR2PDCD1CD274 | |
| SCHEMBL18917226 | 0.87 | AVPR2 (0.42) | AVPR2PDCD1CD274 | |
| SCHEMBL27789681 | 0.85 | PDCD1 (0.38) | AVPR2PDCD1CD274 | |
| SCHEMBL2130987 | 0.84 | AVPR2 (0.51) | AVPR2PDCD1CD274 | |
| SCHEMBL27768190 | 0.82 | PDCD1 (0.39) | AVPR2PDCD1CD274 | |
| SCHEMBL2129539 | 0.81 | AVPR2 (0.49) | AVPR2PDCD1CD274 | |
| SCHEMBL2628070 | 0.79 | PDCD1 (0.52) | AVPR2PDCD1CD274 | |
| SCHEMBL2616280 | 0.77 | PDCD1 (0.49) | AVPR2PDCD1CD274 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1781661-B1 | VASOPRESSIN V1A ANTAGONISTS | VANTIA LTD (GB) | 2017-06-07 | — | — | EP | claimed |